CAJ | 학술논문

目的调查颅脑创伤( TBI)患者外伤性癫痫(PTE)的发生率、发作类型、危险因素及其认知功能等.方法对我院脑系科中心2004年9月至2007年9月之间好转出院的TBI病例进行回顾性调查和电话随访及回访.纳入资料完整及能随访的患者共2 023例.结果 (1)2023例TBI患者中有98例出现PTE,其发生率为4.84％,高发年龄段为51～ 70岁和10岁以下.65例(66.32％)患者的PTE发生于外伤后1年以内；(2)TBI病情重、高龄、皮层损伤、蛛网膜下腔出血、多次手术治疗及受伤早期痫性发作均可增加PTE的发病率；(3) PTE患者认知障碍和性格发生变化的发生率高于非PTE患者(P＜0.05).结论癫痫发生与TBI严重程度、受伤年龄、损伤部位、影像学表现、治疗方法和伤后临床表现等有关.
목적 조사로뇌창상( TBI)환자외상성전간(PTE)적발생솔、발작류형、위험인소급기인지공능등.방법 대아원뇌계과중심2004년9월지2007년9월지간호전출원적TBI병례진행회고성조사화전화수방급회방.납입자료완정급능수방적환자공2 023례.결과 (1)2023례TBI환자중유98례출현PTE,기발생솔위4.84％,고발년령단위51～ 70세화10세이하.65례(66.32％)환자적PTE발생우외상후1년이내；(2)TBI병정중、고령、피층손상、주망막하강출혈、다차수술치료급수상조기간성발작균가증가PTE적발병솔；(3) PTE환자인지장애화성격발생변화적발생솔고우비PTE환자(P＜0.05).결론 전간발생여TBI엄중정도、수상년령、손상부위、영상학표현、치료방법화상후림상표현등유관.
Objective The purpose of this study was to investigate the incidence of posttraumatic seizure and epilepsy,the seizure type of epilepsy,risk factors of epilepsy and Recognition function.Methods The TBI cases discharged after the improvement from September 2004 to September 2007 were retrospectively investigated and visited by telephone and 2023 cases was brought into study.Results ( 1 )98 cases suffered PTE and the incidence of PTE was 4.84％ ; the age of high incidence was 51 ～ 70 years old and less than 10 years old.65 cases (66.32％ ) occurred in less than one year after trauma.(2) Serious injury,old age,cortical injury,subarachnoid hemorrhage,many surgical treatment and early epileptic seizure after injury would increase the incidence of PTE ( P ＜ 0.05 ).( 3 ) The incidence of cognitive impairment was higher in patients with PTE than non - PTE patients ( P ＜ 0.05).Conclusion The risk of posttraumatic seizure and epilepsy is correlation with the severity of TBI,age,injury location,imaging findings,treatment methods and clinical manifestations after injury.