中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2012年
12期
2110-2114
,共5页
任炼%李志忠%隋杰%林永新%焦根龙%孙国栋
任煉%李誌忠%隋傑%林永新%焦根龍%孫國棟
임련%리지충%수걸%림영신%초근룡%손국동
经皮椎体成形%椎体%骨折%骨质疏松%椎体压缩性骨折%远期疗效%生物材料
經皮椎體成形%椎體%骨摺%骨質疏鬆%椎體壓縮性骨摺%遠期療效%生物材料
경피추체성형%추체%골절%골질소송%추체압축성골절%원기료효%생물재료
背景:经皮椎体成形应用于骨质疏松性椎体压缩骨折的治疗已取得很好的效果,但其远期的疗效及对患者的影响至今少有报道.目的:随访分析骨水泥充填椎体成形治疗骨质疏松性椎体压缩骨折的远期疗效.方法:选择骨质疏松性椎体压缩性骨折并行经皮椎体成形治疗的患者34例,对成形前、成形后1周和成形后平均6年进行目测类比评分及标准侧位X射线片上病变椎体高度、脊柱后凸畸形角进行测量与比较,观察成形后远期疗效.结果与结论:成形后1周及平均6年的脊柱后凸畸形角较成形前降低,成形后随访期内变化不明显.成形后椎体高度较成形前明显恢复(P < 0.01);成形后1周及成形后平均6年随访期内椎体高度变化不显著.成形后1周及成形后平均6年的目测类比评分较成形前降低明显(P < 0.01),但随时间延长,目测类比评分有升高趋势.以上各指标在成形后平均6年随访中基本维持稳定.结果证实,椎体成形治疗骨质疏松性椎体压缩骨折安全而有效,远期疗效肯定.
揹景:經皮椎體成形應用于骨質疏鬆性椎體壓縮骨摺的治療已取得很好的效果,但其遠期的療效及對患者的影響至今少有報道.目的:隨訪分析骨水泥充填椎體成形治療骨質疏鬆性椎體壓縮骨摺的遠期療效.方法:選擇骨質疏鬆性椎體壓縮性骨摺併行經皮椎體成形治療的患者34例,對成形前、成形後1週和成形後平均6年進行目測類比評分及標準側位X射線片上病變椎體高度、脊柱後凸畸形角進行測量與比較,觀察成形後遠期療效.結果與結論:成形後1週及平均6年的脊柱後凸畸形角較成形前降低,成形後隨訪期內變化不明顯.成形後椎體高度較成形前明顯恢複(P < 0.01);成形後1週及成形後平均6年隨訪期內椎體高度變化不顯著.成形後1週及成形後平均6年的目測類比評分較成形前降低明顯(P < 0.01),但隨時間延長,目測類比評分有升高趨勢.以上各指標在成形後平均6年隨訪中基本維持穩定.結果證實,椎體成形治療骨質疏鬆性椎體壓縮骨摺安全而有效,遠期療效肯定.
배경:경피추체성형응용우골질소송성추체압축골절적치료이취득흔호적효과,단기원기적료효급대환자적영향지금소유보도.목적:수방분석골수니충전추체성형치료골질소송성추체압축골절적원기료효.방법:선택골질소송성추체압축성골절병행경피추체성형치료적환자34례,대성형전、성형후1주화성형후평균6년진행목측류비평분급표준측위X사선편상병변추체고도、척주후철기형각진행측량여비교,관찰성형후원기료효.결과여결론:성형후1주급평균6년적척주후철기형각교성형전강저,성형후수방기내변화불명현.성형후추체고도교성형전명현회복(P < 0.01);성형후1주급성형후평균6년수방기내추체고도변화불현저.성형후1주급성형후평균6년적목측류비평분교성형전강저명현(P < 0.01),단수시간연장,목측류비평분유승고추세.이상각지표재성형후평균6년수방중기본유지은정.결과증실,추체성형치료골질소송성추체압축골절안전이유효,원기료효긍정.
BACKGROUND: Percutaneous vertebroplasty for osteoporotic vertebral compression fractures has achieved very good results, but its long-term efficacy as well as impact on patients has been rarely reported so far.OBJECTIVE: To investigate the long-term effect of vertebroplasty with bone cement on osteoporotic vertebral compression fractures through a follow-up.METHODS: Thirty-four patients with osteoporotic vertebral compression fractures who had undergone percutaneous vertebroplasty were recruited. Visual analogue scale scoring was measured and compared as well as lesioned vertebral height and kyphosis angle shown on lateral X-ray examination prior to, 1 week and 6 years after percutaneous vertebroplasty.RESULTS AND CONCLUSION: The kyphosis angle was improved 1 week and 6 years after percutaneous vertebroplasty, and it changed insignificantly during the follow-up period. The vertebral height was also improved significantly after percutaneous vertebroplasty (P < 0.01); however, there was no obvious variation in the vertebral height at 1 week and 6 years after percutaneous vertebroplasty. The visual analogue scale exhibited an improvement after percutaneous vertebroplasty (P < 0.01); however, with time going by, the scoring on the visual analogue scale had an increased tend. All the parameters remained stable and had no large fluctuations. It is proved that the percutaneous vertebroplasty is effective and safe to treat osteoporotic vertebral compression fractures with an excellent long-term effect.