中国医药
中國醫藥
중국의약
CHINA MEDICINE
2011年
1期
5-6
,共2页
李十红%李庆祥%卢新%白树功
李十紅%李慶祥%盧新%白樹功
리십홍%리경상%로신%백수공
冠状动脉硬化%青年%抑郁症%相关因素
冠狀動脈硬化%青年%抑鬱癥%相關因素
관상동맥경화%청년%억욱증%상관인소
Coronary heart disease%Youth%Depression%Clinical features%Related factors
目的 探讨青年冠状动脉粥样硬化性心脏病(冠心病)伴抑郁症患者的临床特点、相关因素及预后.方法 选择青年冠心病伴抑郁症患者76例为观察组,青年冠心病不伴抑郁症患者70例为对照组.对2组患者的临床特点、家庭及社会支持以及冠状动脉造影的结果进行分析对比并随访.结果 观察组患者严重睡眠障碍、焦虑激越、情绪低落、兴趣减退、自觉无用负罪感等症状的发生率与对照组比较差异有统计学意义.对照组的家庭和睦及社会支持率明显高于观察组(64.3%比26.3%,P＜0.01).动脉造影显示,观察组与对照组患者冠状动脉病变程度无明显差异.随访急性冠状动脉综合征(ACS)发生率、再住院率等指标观察组均明显高于对照组(15.8%比1.4%,36.8%比12.9%,P＜0.05).结论 青年冠心病伴抑郁症患者易产生严重睡眠障碍、焦虑激越、情绪低落、兴趣减退等症状;ACS发生率明显增高;临床要高度重视青年冠心病伴发抑郁症,积极识别及时治疗,有助青年冠心病患者预后改善,社会及家庭意义重大.
目的 探討青年冠狀動脈粥樣硬化性心髒病(冠心病)伴抑鬱癥患者的臨床特點、相關因素及預後.方法 選擇青年冠心病伴抑鬱癥患者76例為觀察組,青年冠心病不伴抑鬱癥患者70例為對照組.對2組患者的臨床特點、傢庭及社會支持以及冠狀動脈造影的結果進行分析對比併隨訪.結果 觀察組患者嚴重睡眠障礙、焦慮激越、情緒低落、興趣減退、自覺無用負罪感等癥狀的髮生率與對照組比較差異有統計學意義.對照組的傢庭和睦及社會支持率明顯高于觀察組(64.3%比26.3%,P＜0.01).動脈造影顯示,觀察組與對照組患者冠狀動脈病變程度無明顯差異.隨訪急性冠狀動脈綜閤徵(ACS)髮生率、再住院率等指標觀察組均明顯高于對照組(15.8%比1.4%,36.8%比12.9%,P＜0.05).結論 青年冠心病伴抑鬱癥患者易產生嚴重睡眠障礙、焦慮激越、情緒低落、興趣減退等癥狀;ACS髮生率明顯增高;臨床要高度重視青年冠心病伴髮抑鬱癥,積極識彆及時治療,有助青年冠心病患者預後改善,社會及傢庭意義重大.
목적 탐토청년관상동맥죽양경화성심장병(관심병)반억욱증환자적림상특점、상관인소급예후.방법 선택청년관심병반억욱증환자76례위관찰조,청년관심병불반억욱증환자70례위대조조.대2조환자적림상특점、가정급사회지지이급관상동맥조영적결과진행분석대비병수방.결과 관찰조환자엄중수면장애、초필격월、정서저락、흥취감퇴、자각무용부죄감등증상적발생솔여대조조비교차이유통계학의의.대조조적가정화목급사회지지솔명현고우관찰조(64.3%비26.3%,P＜0.01).동맥조영현시,관찰조여대조조환자관상동맥병변정도무명현차이.수방급성관상동맥종합정(ACS)발생솔、재주원솔등지표관찰조균명현고우대조조(15.8%비1.4%,36.8%비12.9%,P＜0.05).결론 청년관심병반억욱증환자역산생엄중수면장애、초필격월、정서저락、흥취감퇴등증상;ACS발생솔명현증고;림상요고도중시청년관심병반발억욱증,적겁식별급시치료,유조청년관심병환자예후개선,사회급가정의의중대.
Objective To study the clinical characteristics of young coronary heart disease (CHD)patients suffering from depression. Methods The clinical data of 76 young CHD patients with depression (depression group) and 70 young CHD patients without depression (none-depression group)were enrolled. Clinical characteristics, family and social support, coronary angiography results of the two groups were followed up and compared.Results Severe sleep disorders, anxiety, agitation, depression in depression group were significantly higher than those in none-depression group ( P ＜ 0.05 ). Family harmony and social support in depression group were significantly lower than those in none-depression group ( P ＜ 0. 01 ). Angiography showed no significant difference between the 2 groups. Re-admission rate was significantly higher due to acute coronary syndrome (ACS) in depression group (P ＜0.05). Conclusions Young CHD patients with depression have high chance of suffering from sleep disorder,anxiety, agitation, depression, diminished interest and other complications such as ACS. Early identification and aggressive treatment can help improve the prognosis of young patients CHD with depression.
