CAJ | 학술논문

目的:探讨全肺放疗治疗肺转移癌的价值.方法:1999年3月～2003年5月我院肿瘤科收治24例双肺多发肺转移癌患者,均给予全肺放疗.现对这些患者的临床资料进行总结分析.结果:本组放疗结束时转移瘤CR率为37.5%(9/24),PR率为50.0%(12/24),有效率(PR+CR)达87.5%.原发肿瘤为鼻咽癌、乳腺癌、肝癌、结直肠癌的中位生存期分别为13.5、22.0、10.5月、8.5月.1～2级放射性肺炎发生率为25.0%(6/24);3级为16.7%(2/24);4～5级为0.结论:恶性肿瘤肺多发转移可以采用全肺放疗+局部小野补量治疗,尤其适用于原发肿瘤对放疗中高度敏感、化疗无效的患者,可获得较好疗效.毒副作用可耐受.
목적:탐토전폐방료치료폐전이암적개치.방법:1999년3월～2003년5월아원종류과수치24례쌍폐다발폐전이암환자,균급여전폐방료.현대저사환자적림상자료진행총결분석.결과:본조방료결속시전이류CR솔위37.5%(9/24),PR솔위50.0%(12/24),유효솔(PR+CR)체87.5%.원발종류위비인암、유선암、간암、결직장암적중위생존기분별위13.5、22.0、10.5월、8.5월.1～2급방사성폐염발생솔위25.0%(6/24);3급위16.7%(2/24);4～5급위0.결론:악성종류폐다발전이가이채용전폐방료+국부소야보량치료,우기괄용우원발종류대방료중고도민감、화료무효적환자,가획득교호료효.독부작용가내수.
Objective:To investigate the whole-lung irradiation value on the pulmonary metastases.Methods:From March 1999 to May 2003, there were 24 patients with multiple double-pulmonary metastases accepted whole-lung irradiation in the department of oncology, Jiangmen center hospital. Data of the 24 patients were retrospectively analyzed. Results:After radiotherapy, the complete response rate of lung transferring tumor was 37.5% (9/24), partial response rate was 50.0% (12/24) and the overall response rate (PR+CR) was 87.5%. As the primary tumor was nasopharyngeal carcinoma, breast cancer, liver cancer, colonic and rectal cancer, the median survival time was 13.5, 22.0, 10.5, 8.5 months, respectively. Grade 1-2 radiation pneumonitis were 25.0%(6/24), grade 3 were 16.7%(2/24), grade 4-5 were 0. Conclusion:Whole-lung irradiation plus local boost is able to treat pulmonary metastases of malignant tumor. It's applicable especially to the patient whose primary tumor is sensitive to radiotherapy and no response to chemotherapy. The curative effect is satisfaction and the side effects are acceptable.