CAJ | 학술논문

目的:探讨耳鼻咽喉头颈部原发性结外非霍奇金淋巴瘤(NHL)的临床病理学特征.方法:回顾性分析216例头颈部NHL患者的临床病理学资料.结果:本组样本年龄分布有2个高发段,分别为31~60岁和71~80岁;最常见的原发部位为鼻腔95例(44.0%),其次为扁桃体47例(21.8%);最常见的组织学类型为NK/T细胞淋巴瘤107例(49.5%),其次为弥漫性大B细胞淋巴瘤58例(26.7%).按部位统计发病率最高的组织学类型分别为:鼻腔为NK/T细胞淋巴瘤74例(77.9%),鼻窦为弥漫性大B细胞淋巴瘤6例(50.0%),扁桃体为弥漫性大B细胞淋巴瘤27例(57.4%),鼻咽口咽为NK/T细胞淋巴瘤17例(44.7%),舌根为弥漫大B细胞淋巴瘤5例(45.4%).结论:耳鼻咽喉头颈部原发性NHL是一类比较常见的疾病,其在发病年龄、原发部位和组织学类型上都具有明显的临床病理学特征,对临床病理诊断有较大的帮助.
목적:탐토이비인후두경부원발성결외비곽기금림파류(NHL)적림상병이학특정.방법:회고성분석216례두경부NHL환자적림상병이학자료.결과:본조양본년령분포유2개고발단,분별위31~60세화71~80세;최상견적원발부위위비강95례(44.0%),기차위편도체47례(21.8%);최상견적조직학류형위NK/T세포림파류107례(49.5%),기차위미만성대B세포림파류58례(26.7%).안부위통계발병솔최고적조직학류형분별위:비강위NK/T세포림파류74례(77.9%),비두위미만성대B세포림파류6례(50.0%),편도체위미만성대B세포림파류27례(57.4%),비인구인위NK/T세포림파류17례(44.7%),설근위미만대B세포림파류5례(45.4%).결론:이비인후두경부원발성NHL시일류비교상견적질병,기재발병년령、원발부위화조직학류형상도구유명현적림상병이학특정,대림상병리진단유교대적방조.
Objective:To study the clinicopathologic characteristic of the primary extranodular non-Hodgkin's lymphoma in head and neck.Method:Clinical manifestation and the characteristic of clinicopathology of 216 extranodular non-Hodgkin's lymphoma patients in head and neck were analyzed retrospectively.Result:The age of thirty-one to sixty and seventy-one to eighty years old were more common age range in the group of patients. Nasal cavity was the most commonly primary involved site(95 cases, 44.0% ) , secondly was tonsil ( 47 cases, 21.8%). The most common histologic subtype was NK/T cell lymphoma, which accounted for 49.5%(107 cases)of cases, secondly was diffuse large B cell lymphoma (DLBCL, 58 cases, 26.7%). The most common histologic subtype in different swtach groups respectively is: NK/T cell lymphoma in nasal cavity(74 cases,77.9%), DLBCL in paranasal sinus(6 cases,50.0%), DLBCL in tonsil(27 cases,57.4%),NK/T cell lymphoma in nasopharynx(17 cases,44.7%), and DLBCL in lingual root(5 cases,45.4%).Conclusion:We conclude that primary extranodular non-Hodgkin's lymphoma is common in head and neck patients. There is characteristic in age, primary involved site and histologic subtype, which is helpful to understand these characteristic for pathologic diagnosis.