CAJ | 학술논문

目的探索防治结核性胸膜炎胸膜肥厚成本低、效果好的治疗方法 .方法 64例中至大量游离结核性胸腔积液患者随机分为治疗组和对照组.治疗组胸腔置管完全引流积液后注入透明质酸钠,对照组常规胸穿抽液.统计治疗3个月后2组花费的成本,进行成本效果分析及敏感度分析.结果 59例患者参与最后结果分析.治疗3个月后治疗组、对照组胸膜肥厚发生率是6.7%、31.0%(有效率分别是:93.3%、69.0%)(P<0.05);成本效果比(C/E)是35.19,47.53,敏感度分析显示C/E35.63,49.00.结论胸腔置管联合透明质酸钠防治结核性胸膜炎胸膜肥厚是成本低、效果好的方法 .
목적 탐색방치결핵성흉막염흉막비후성본저、효과호적치료방법 .방법 64례중지대량유리결핵성흉강적액환자수궤분위치료조화대조조.치료조흉강치관완전인류적액후주입투명질산납,대조조상규흉천추액.통계치료3개월후2조화비적성본,진행성본효과분석급민감도분석.결과 59례환자삼여최후결과 분석.치료3개월후치료조、대조조흉막비후발생솔시6.7%、31.0%(유효솔분별시:93.3%、69.0%)(P<0.05);성본효과비(C/E)시35.19,47.53,민감도분석현시C/E35.63,49.00.결론 흉강치관연합투명질산납방치결핵성흉막염흉막비후시성본저、효과호적방법 .
Objective To explore the method of lower cost and better results, to prevent pleural thiekening(PT) of tuberculous pleurisy. Methods Sixty-four patients with middle to large pleru-ral effusions were randomly assigned to a treatment group and a control group. Patients in treat-ment group given with sodium hyaluronate via central venous catheter into the thoracic cavity after pleural effusion was drainaged completely,while patients in control group received routine thoraeen-tesis. We calculated the cost after 3 months in two groups respectively and analyzed the cost-effec-tiveness and sensitivity. Results Fifty-nine patients were available for final analysis. The inci-dence rate of PT at 3rd month were 6.7% in treatment group and 31.0% in control group(the effec-tive rate: 93.3% vs. 69.0%, respectively) with statistically significant difference(P<0.05) ; The cost/effective rate were 35.2 in the treatment group and 47. 5 in the control group. Sensitivity anal-ysis showed 35.6 in the treatment group and 49.00 in the control group. Conclusions Intrathorac-ic cannula combining with administration of sodium hyaluronate is a method of lower cost and better results to prevent pleural thickening of tuberculous pleurisy.