中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
8期
1009-1010
,共2页
地佐辛%芬太尼%瑞芬太尼%宫腔镜手术
地佐辛%芬太尼%瑞芬太尼%宮腔鏡手術
지좌신%분태니%서분태니%궁강경수술
Dezocine%Fentanyl%Remifentanil%Hysteroscopic operation
目的 比较地佐辛复合丙泊酚用于宫腔镜手术麻醉的效果与安全性.方法 选择宫腔镜检查+分段诊刮及电切术90例,随机分为芬太尼组、瑞芬太尼组和地佐辛组各30例.瑞芬太尼组持续静脉输注瑞芬太尼0.1μg/(kg·min),2 min后静脉注射丙泊酚1.5 mg/kg.芬太尼组先静脉注射芬太尼1μg/kg,2 min后再静脉注射丙泊酚1.5 mg/kg.地佐辛组先静脉注射地佐辛0.1 mg/kg,2 min后再静脉注射丙泊酚1.5 mg/kg.观察并记录3组麻醉效果,循环、呼吸、血氧饱和度(Sp02)变化情况,起效时间,苏醒时间,丙泊酚用量,记录麻醉效果及不良反应.结果 地佐辛组低血压、心动过缓发生率低于瑞芬太尼组、芬太尼组[3.3％(1/30)比16.7％ (5/30)、10.0％ (3/30)；0比10.0％ (3/30)、6.7％(2/30),均P＜0.05].瑞芬太尼组较地佐辛组、芬太尼组呼吸抑制明显(P＜0.05).3组镇痛效果差异无统计学意义(P＞0.05),芬太尼组相对地佐辛组、瑞芬太尼组丙泊酚用量最大[(193±13)mg比(160±14)mg,(140±12)mg,P＜0.05].结论 地佐辛复合丙泊酚应用于宫腔镜手术安全有效.
目的 比較地佐辛複閤丙泊酚用于宮腔鏡手術痳醉的效果與安全性.方法 選擇宮腔鏡檢查+分段診颳及電切術90例,隨機分為芬太尼組、瑞芬太尼組和地佐辛組各30例.瑞芬太尼組持續靜脈輸註瑞芬太尼0.1μg/(kg·min),2 min後靜脈註射丙泊酚1.5 mg/kg.芬太尼組先靜脈註射芬太尼1μg/kg,2 min後再靜脈註射丙泊酚1.5 mg/kg.地佐辛組先靜脈註射地佐辛0.1 mg/kg,2 min後再靜脈註射丙泊酚1.5 mg/kg.觀察併記錄3組痳醉效果,循環、呼吸、血氧飽和度(Sp02)變化情況,起效時間,囌醒時間,丙泊酚用量,記錄痳醉效果及不良反應.結果 地佐辛組低血壓、心動過緩髮生率低于瑞芬太尼組、芬太尼組[3.3％(1/30)比16.7％ (5/30)、10.0％ (3/30)；0比10.0％ (3/30)、6.7％(2/30),均P＜0.05].瑞芬太尼組較地佐辛組、芬太尼組呼吸抑製明顯(P＜0.05).3組鎮痛效果差異無統計學意義(P＞0.05),芬太尼組相對地佐辛組、瑞芬太尼組丙泊酚用量最大[(193±13)mg比(160±14)mg,(140±12)mg,P＜0.05].結論 地佐辛複閤丙泊酚應用于宮腔鏡手術安全有效.
목적 비교지좌신복합병박분용우궁강경수술마취적효과여안전성.방법 선택궁강경검사+분단진괄급전절술90례,수궤분위분태니조、서분태니조화지좌신조각30례.서분태니조지속정맥수주서분태니0.1μg/(kg·min),2 min후정맥주사병박분1.5 mg/kg.분태니조선정맥주사분태니1μg/kg,2 min후재정맥주사병박분1.5 mg/kg.지좌신조선정맥주사지좌신0.1 mg/kg,2 min후재정맥주사병박분1.5 mg/kg.관찰병기록3조마취효과,순배、호흡、혈양포화도(Sp02)변화정황,기효시간,소성시간,병박분용량,기록마취효과급불량반응.결과 지좌신조저혈압、심동과완발생솔저우서분태니조、분태니조[3.3％(1/30)비16.7％ (5/30)、10.0％ (3/30)；0비10.0％ (3/30)、6.7％(2/30),균P＜0.05].서분태니조교지좌신조、분태니조호흡억제명현(P＜0.05).3조진통효과차이무통계학의의(P＞0.05),분태니조상대지좌신조、서분태니조병박분용량최대[(193±13)mg비(160±14)mg,(140±12)mg,P＜0.05].결론 지좌신복합병박분응용우궁강경수술안전유효.
Objective To investigate the feasibility and safety of dezocine and propofol intravenous anesthesia for hysteroscopy fractional curettage hysteroscopes electrotomy.Methods Ninety patients with hysteroscopy fractional curettage hysterscopes selectrotomy were randomly divided into three groups:propofol combined with dezocine,propofol combined with fentanyl,propofol combined with remifentanil.Anesthesia effect,recovery time,body movement,respiratory depression,and the incidence of adverse reactions after surgery and the total amount of propofol were recorded.Results The incidence rate of low blood pressure and brady in the dezocine group had significant differences [3.3％ (1/30)vs 16.7％ (5/30),10.0％ (3/30);0 vs 10.0％ (3/30),6.7％ (2/30),all P ＜0.05].The respiratory depression of remifentanil groups had significant differences (P ＜ 0.05).The anesthesia effect,in three groups had no significant differences (P ＞ 0.05); the total amount of propofol in the fentanyl group had significant differences[(193 ± 13)mg vs (160 ± 14)mg,(140 ± 12)mg].The remifentanil groups of patients with anesthesia effect after operation had significant differences(P ＜ 0.05).Conclusions Dezocine and propofol for hysteroscopes electrotomy can be used safely.Propofol combined with dezocine is the best among all the three groups.
