CAJ | 학술논문

目的探讨颈动脉正常和斑块部佗、硬斑块和软斑块及斑块的肩部和纤维帽顶部速度、应变及应变率变化规律.方法对86例冠心病伴颈动脉粥样斑块患者和50例正常人双侧颈动脉进行高频超声检查,检测颈动脉内膜-中层厚度(IMT);应用速度向量成像(VVI)斑点追踪技术检测颈动脉的运动速度、应变、应变率,并分组进行分析.结果冠心病组颈动脉IMT高于正常组,差异有统计学意义(P＜0.05);正常对照组颈动脉收缩期径向最大运动速度高于冠心病颈动脉无斑块部位的测值,差异有统计学意义(P＜0.05);软斑块收缩期最大运动速度、最大应变率高于硬斑块组,差异有统计学意义(P＜0.001或P＜0.05);颈动脉斑块肩部收缩期最大运动速度、应变率高于斑块纤维帽顶部.差异有统计学意义(P＜0.05或P＜0.001).结论 VVI技术可早期检测血管壁的弹性度,早期检测颈动脉荆样硬化及颈动脉粥样硬化斑块部位内膜运动的机械不一致性和不同部位的力学指标差别,有可能作为动脉粥样硬化不稳定斑块的初查和量化评价指标.
목적 탐토경동맥정상화반괴부타、경반괴화연반괴급반괴적견부화섬유모정부속도、응변급응변솔변화규률.방법대86례관심병반경동맥죽양반괴환자화50례정상인쌍측경동맥진행고빈초성검사,검측경동맥내막-중층후도(IMT);응용속도향량성상(VVI)반점추종기술검측경동맥적운동속도、응변、응변솔,병분조진행분석.결과관심병조경동맥IMT고우정상조,차이유통계학의의(P＜0.05);정상대조조경동맥수축기경향최대운동속도고우관심병경동맥무반괴부위적측치,차이유통계학의의(P＜0.05);연반괴수축기최대운동속도、최대응변솔고우경반괴조,차이유통계학의의(P＜0.001혹P＜0.05);경동맥반괴견부수축기최대운동속도、응변솔고우반괴섬유모정부.차이유통계학의의(P＜0.05혹P＜0.001).결론 VVI기술가조기검측혈관벽적탄성도,조기검측경동맥형양경화급경동맥죽양경화반괴부위내막운동적궤계불일치성화불동부위적역학지표차별,유가능작위동맥죽양경화불은정반괴적초사화양화평개지표.
Objective To assess the changes of the velocity,strain and strain rate on the corresponding vascular of plaque and without plaque,bard plaque and soft plaque,the cupular part of fiber cowl and shoulder of plaque.Methods Eighty-six patients with coronary artery disease(CAD)according to the results of coronary arteriography and 50 normal subjects underwent the high frequency ultrasound,and carotid artery intima media thickness(IMT)was detected.The velocity,strain and stain rate of carotid were obtained by velocity vector imaging(VVI)speckle tracking technique.Results The level of IMT in CAD patients was higher than that in normal control(P＜0.05).The systolic maximum velocity of carotid with normal contract was higher significantly than that of carotid without plaque with CAD(P＜0.05).The systolic maximum velocity and strain rate of soft plaque in carotid atherosclerosis were higher significantly than those of hard plaque(P＜0.001,P＜0.05).The maximum velocity and strain rate of fabric cowl in carotid atheroscIerosis plaque were lower significantly than those of plaque shoulder(P＜0.05,P＜0.00 1).Conclusions VVI technique could early detect the elasticity degree of blood vessel wall,artherosclerosis and the mechanism asynchrony of the plaque intima.The value difference could be used as the predictive parameter and quantization for artherosclerosis and plaque instability.