CAJ | 학술논문

AIY神经元作为线虫重要的中间神经元,一般认为在线虫的温度感受中发挥功能.分别进行的苯甲醛和硫酸铜的趋向性实验显示,AIY在线虫对于这两种化学物质的感受过程中起作用,而且对于硫酸铜的感受行使抑制功能.苯甲醛和硫酸铜的抉择实验显示,AIY在线虫中能够对这两种物质引起的信号进行整合,在ttx-3突变体中AIY神经元仍然可以行使整合的功能.但是无法判断该整合的功能是否完全无缺陷.
AIY신경원작위선충중요적중간신경원,일반인위재선충적온도감수중발휘공능.분별진행적분갑철화류산동적추향성실험현시,AIY재선충대우저량충화학물질적감수과정중기작용,이차대우류산동적감수행사억제공능.분갑철화류산동적결택실험현시,AIY재선충중능구대저량충물질인기적신호진행정합,재ttx-3돌변체중AIY신경원잉연가이행사정합적공능.단시무법판단해정합적공능시부완전무결함.
As one of the most important interneurons, AIY plays an important role for the thermosensation in C. elegans and serves as the postsynaptic part of many sensory neurons. Individual chemotaxis assay of benzaldehyde and CuSO_4 revealed that AIY was involved in the processes of chemosensation in C. elegans. Chemotactic choice assay in Cu~(2+)/ benzaldehyde paradigms suggested that the AIY participated in the combination of the chemosensation in wild type, even in the ttx-3mutant. Further work needs to be done to explore if the combination function of AIY is intact in the ttx-3 mutant.