癌变·畸变·突变
癌變·畸變·突變
암변·기변·돌변
CARCINOGENSES,TERATOGENSIS AND MUTAGENESIS
2010年
2期
119-122
,共4页
邵小翠%朴丰源%关怀%李小薇%徐蕾%横山和仁
邵小翠%樸豐源%關懷%李小薇%徐蕾%橫山和仁
소소취%박봉원%관부%리소미%서뢰%횡산화인
铊%影响因素%母血%脐血
鉈%影響因素%母血%臍血
사%영향인소%모혈%제혈
thallium%influence factors%cord blood%maternal blood
目的:检测分析大连地区母血和脐血中铊浓度及其相关影响因素,为孕期合理保健提供资料. 方法:收集125对母血及脐血,采用电感耦合等离子体-质谱(ICP-MS)法测定其血中铊的浓度,同时就孕妇家庭和社会环境等因素对血铊浓度的影响进行单因素分析和多元线性回归分析. 结果:大连地区母血和脐血中铊的浓度分别为48.8±29.9 ng/L和42.0±29.2 ng/L,两者间的差异具有统计学意义(P<0.05).且母血和脐血的铊浓度之间呈正相关(r=0.731).母血铊浓度因居住地和饮水来源、有无被动吸烟、有无妊娠并发症、是否近期家庭装修等因素的不同而存在差异;多元线性回归分析结果显示,其中饮水来源、有无被动吸烟和有无妊娠并发症等3个因素进入回归方程. 结论:大连地区孕妇及其胎儿均受到铊暴露,居住地、妊娠并发证、被动吸烟、饮水来源、家庭装修等因素均影响母血铊浓度.
目的:檢測分析大連地區母血和臍血中鉈濃度及其相關影響因素,為孕期閤理保健提供資料. 方法:收集125對母血及臍血,採用電感耦閤等離子體-質譜(ICP-MS)法測定其血中鉈的濃度,同時就孕婦傢庭和社會環境等因素對血鉈濃度的影響進行單因素分析和多元線性迴歸分析. 結果:大連地區母血和臍血中鉈的濃度分彆為48.8±29.9 ng/L和42.0±29.2 ng/L,兩者間的差異具有統計學意義(P<0.05).且母血和臍血的鉈濃度之間呈正相關(r=0.731).母血鉈濃度因居住地和飲水來源、有無被動吸煙、有無妊娠併髮癥、是否近期傢庭裝脩等因素的不同而存在差異;多元線性迴歸分析結果顯示,其中飲水來源、有無被動吸煙和有無妊娠併髮癥等3箇因素進入迴歸方程. 結論:大連地區孕婦及其胎兒均受到鉈暴露,居住地、妊娠併髮證、被動吸煙、飲水來源、傢庭裝脩等因素均影響母血鉈濃度.
목적:검측분석대련지구모혈화제혈중사농도급기상관영향인소,위잉기합리보건제공자료. 방법:수집125대모혈급제혈,채용전감우합등리자체-질보(ICP-MS)법측정기혈중사적농도,동시취잉부가정화사회배경등인소대혈사농도적영향진행단인소분석화다원선성회귀분석. 결과:대련지구모혈화제혈중사적농도분별위48.8±29.9 ng/L화42.0±29.2 ng/L,량자간적차이구유통계학의의(P<0.05).차모혈화제혈적사농도지간정정상관(r=0.731).모혈사농도인거주지화음수래원、유무피동흡연、유무임신병발증、시부근기가정장수등인소적불동이존재차이;다원선성회귀분석결과현시,기중음수래원、유무피동흡연화유무임신병발증등3개인소진입회귀방정. 결론:대련지구잉부급기태인균수도사폭로,거주지、임신병발증、피동흡연、음수래원、가정장수등인소균영향모혈사농도.
OBJECTIVE: To examine thallium levels of maternal and umbilical cord blood, and analyze some relevant influencing factors. METHODS: We selected 125 pregnant women. Their venous bloods were drawn and subject to the microwave digestion method. The concentration of blood thallium was determined by ICP-MS. The effects of the relevant factors, including family condition and social environment of each pregnant woman, on the concentration of blood thallium were analyzed. The average thallium levels of maternal and umbilical cord blood were 48.8 ~29.9 ng/L and 42.0~9.2 ng/L, respectively, the correlation coefficient was 0.731. Several factors were found to be related to the thallium concentration of maternal blood, such as place of residence, source of drinking water, passive smoking, home renovation (P< 0.05). The results of multiple linear regression analysis of the relevant influencing factors were source of drinking water, passive smoking, complications of pregnancy. CONCLUSION: Place of residence, passive smoking, source of drinking water, home renovation were the factors affecting the thallium level of maternal blood (P<0.05).