CAJ | 학술논문

目的观察血府逐瘀汤联合替米沙坦治疗2型糖尿病肾病的疗效.方法选择2型糖尿病肾病患者80例,随机分为两组,对照组40例接受常规治疗和替米沙坦40～80mg/d,治疗组在对照组治疗基础上加服血府逐瘀汤加减方剂治疗,比较两组的疗效及各项生化指标.结果治疗组疗效优于对照组,差异有统计学意义(P<0.05),治疗组经治疗后尿蛋白排泄率,24h尿蛋白定量、血肌酐、血尿素氮下降,与对照组治疗后比较,差异有统计学意义(P<0.05).结论血府逐瘀汤联合替米沙坦治疗糖尿病肾病其改善肾功能和疗效作用优于单用替米沙坦治疗.
목적 관찰혈부축어탕연합체미사탄치료2형당뇨병신병적료효.방법 선택2형당뇨병신병환자80례,수궤분위량조,대조조40례접수상규치료화체미사탄40～80mg/d,치료조재대조조치료기출상가복혈부축어탕가감방제치료,비교량조적료효급각항생화지표.결과 치료조료효우우대조조,차이유통계학의의(P<0.05),치료조경치료후뇨단백배설솔,24h뇨단백정량、혈기항、혈뇨소담하강,여대조조치료후비교,차이유통계학의의(P<0.05).결론 혈부축어탕연합체미사탄치료당뇨병신병기개선신공능화료효작용우우단용체미사탄치료.
Objective To observe the clinical efficacy of Xuefuzhuyu decoction combined with telmisartan on Diabetic Nephropathy(DN).Methods Eighty DN patients were randomly divided into treatment group(n=40)and control group(n=40).The control group was treated with routine treatment plus telmisartan 40ms-80mg/day and the treatment group with Xuefuzhuyu decoction besides it.Results The effect was more evident in treatment group than in control group(P<0.05).After treatment,urinary albumin excretion rate、24h urinary protein、serum creatinine、blood urea nitroger were decreased in both decoction combined with telmisartan can improve the clinical symptoms and renal function in DN patients.The efficacy is superior to simple with telmisartan.