心血管病学进展
心血管病學進展
심혈관병학진전
ADVANCES IN CARDIOVASCULAR DISEASES
2010年
2期
193-196
,共4页
高血压%肥胖%治疗
高血壓%肥胖%治療
고혈압%비반%치료
hypertension%obesity%treatment
肥胖相关性高血压临床常见,但治疗困难,包括控制体重和降低血压.控制体重的措施包括饮食控制、体育锻炼、行为治疗、减肥药物及外科手术.患者通常需要联合使用多种降压药物,初始治疗可选择阻断肾素-血管紧张素系统的药物.咪唑啉激动剂等新药正在研究中,植入压力感受器调节装置及肾交感神经消融术等非药物降压方法或可用于顽固性高血压患者.
肥胖相關性高血壓臨床常見,但治療睏難,包括控製體重和降低血壓.控製體重的措施包括飲食控製、體育鍛煉、行為治療、減肥藥物及外科手術.患者通常需要聯閤使用多種降壓藥物,初始治療可選擇阻斷腎素-血管緊張素繫統的藥物.咪唑啉激動劑等新藥正在研究中,植入壓力感受器調節裝置及腎交感神經消融術等非藥物降壓方法或可用于頑固性高血壓患者.
비반상관성고혈압림상상견,단치료곤난,포괄공제체중화강저혈압.공제체중적조시포괄음식공제、체육단련、행위치료、감비약물급외과수술.환자통상수요연합사용다충강압약물,초시치료가선택조단신소-혈관긴장소계통적약물.미서람격동제등신약정재연구중,식입압력감수기조절장치급신교감신경소융술등비약물강압방법혹가용우완고성고혈압환자.
The treatment of hypertension in obese individuals is complicated by their poor response to therapeutic treatments and the necessary reduction of weight.The methods to reduce body weight are composed of dietary intervention,physical activity,behavior modification,anti-obesity drugs and bariatric surgery.Antihypertensive drug combination therapy is usually required,and several lines of evidence suggest that drugs blocking renin-angiotensin system might be the first choice.New antihypertensive drugs such as imidazoline agonists and nonpharmacological blood-lowering therapies such as implanted baroreceptor regulation and renal sympathetic nerve ablation are under development.
