南京师大学报（自然科学版）
南京師大學報（自然科學版）
남경사대학보（자연과학판）
JOURNAL OF NANJING NORMAL UNIVERSITY (NATURAL SCIENCE EDITION)
2008年
2期
59-64
,共6页
宋开玺%周家宏%吴晓红%周林%顾晓天%魏少华%冯玉英%王雪松
宋開璽%週傢宏%吳曉紅%週林%顧曉天%魏少華%馮玉英%王雪鬆
송개새%주가굉%오효홍%주림%고효천%위소화%풍옥영%왕설송
竹红菌甲素%溶菌酶%结合作用%光诱导电子转移
竹紅菌甲素%溶菌酶%結閤作用%光誘導電子轉移
죽홍균갑소%용균매%결합작용%광유도전자전이
hypocrellin A%lysozyme%binding interaction%photoinduced electron transfer
在光动力疗法中,竹红菌甲素作为敏剂与溶菌酶发生了相互作用.本文对竹红菌甲素同溶菌酶作用的荧光猝灭机理进行了研究.结果表明,竹红菌甲素与溶菌酶结构中的酪氨酸和色氨酸之间的光诱导电子转移机制,在荧光猝灭过程中起了重要作用.
在光動力療法中,竹紅菌甲素作為敏劑與溶菌酶髮生瞭相互作用.本文對竹紅菌甲素同溶菌酶作用的熒光猝滅機理進行瞭研究.結果錶明,竹紅菌甲素與溶菌酶結構中的酪氨痠和色氨痠之間的光誘導電子轉移機製,在熒光猝滅過程中起瞭重要作用.
재광동력요법중,죽홍균갑소작위민제여용균매발생료상호작용.본문대죽홍균갑소동용균매작용적형광졸멸궤리진행료연구.결과표명,죽홍균갑소여용균매결구중적락안산화색안산지간적광유도전자전이궤제,재형광졸멸과정중기료중요작용.
Based on the known binding interaction between lysozyme and hypocrellin A, a photosensitizing drug used in photodynamic therapy, and the fluorescence quenching mechanism of lysozyme by hypocrellin A was studied. The results indicated that the photoinduced electron transfer between the tryptophan and tyrosine residues of lysozyme and hypocrel-lin A plays an important role in this fluorescence quenching process.
