国际生物制品学杂志
國際生物製品學雜誌
국제생물제품학잡지
INTERNATIONAL JOURNAL OF BIOLOGICALS
2012年
1期
21-24
,共4页
流感病毒A型%流感疫苗%模型,动物%交叉免疫
流感病毒A型%流感疫苗%模型,動物%交扠免疫
류감병독A형%류감역묘%모형,동물%교차면역
Influenza A virus%Influenza vaccines%Models,animal%Cross-immunity
流感是重大的公共卫生问题,可发生全球大流行.研制安全有效的流感疫苗对控制流感至关重要.然而,由于流感病毒的交叉免疫及其机制尚未完全阐明,对研制疫苗带来不利影响.对甲型流感病毒交叉免疫的深入研究必将有助于更好地研制流感疫苗,对预防和控制甲型流感具有重要意义.此文对甲型流感病毒交叉免疫、免疫机制、不同亚型免疫的评价等研究进展进行综述.
流感是重大的公共衛生問題,可髮生全毬大流行.研製安全有效的流感疫苗對控製流感至關重要.然而,由于流感病毒的交扠免疫及其機製尚未完全闡明,對研製疫苗帶來不利影響.對甲型流感病毒交扠免疫的深入研究必將有助于更好地研製流感疫苗,對預防和控製甲型流感具有重要意義.此文對甲型流感病毒交扠免疫、免疫機製、不同亞型免疫的評價等研究進展進行綜述.
류감시중대적공공위생문제,가발생전구대류행.연제안전유효적류감역묘대공제류감지관중요.연이,유우류감병독적교차면역급기궤제상미완전천명,대연제역묘대래불리영향.대갑형류감병독교차면역적심입연구필장유조우경호지연제류감역묘,대예방화공제갑형류감구유중요의의.차문대갑형류감병독교차면역、면역궤제、불동아형면역적평개등연구진전진행종술.
Influenza is an important public health problem and occurs globally.Development ofeffective and safe influenza vaccines is vital to control and prevention of influenza.However,cross-protectiveimnmunity to influenza A virus and its mechanisms are not completely elucidated,which results in some negativeinfluences on vaccine development.Further studies on the cross-protective immunity will be helpful toreinforcing development of influenza vaccines,and prevention and control of influenza A.This article reviewsresearch advances in cross-immunity to influenza A virus in animals and humans,cross-immunity mechanisms,and assessment of heterotypic immunity.
