中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
20期
2761-2762
,共2页
胎膜早破%绒毛膜羊膜炎%C反应蛋白%白细胞介素-6
胎膜早破%絨毛膜羊膜炎%C反應蛋白%白細胞介素-6
태막조파%융모막양막염%C반응단백%백세포개소-6
Premature rupture of membranes%Chorioamnionitis%C-reactive protein%Interleukin-6
目的 探讨检测母血白细胞介素-6(IL-6)及C反应蛋白(CRP)对因胎膜早破(PROM)而导致的绒毛膜羊膜炎(CMA)早期预测的意义.方法 采集胎膜早破孕妇的血清测定IL-6及CRP含量,并对产妇的胎盘及胎膜采样进行病理检查.结果 (1)PROM合并CMA者,母血IL-6、CRP含量明显升高(P＜0.01).(2)随着破膜时间的延长,母血IL-6及CRP的水平明显升高(P＜0.01).(3)母血IL-6≥11 ng/L、CRP≥10 mg/L为预测诊断PROM合并早期CMA的阳性率高.结论 母血IL-6及CRP水平的监测对PROM合并CMA有一定的早期诊断意义.
目的 探討檢測母血白細胞介素-6(IL-6)及C反應蛋白(CRP)對因胎膜早破(PROM)而導緻的絨毛膜羊膜炎(CMA)早期預測的意義.方法 採集胎膜早破孕婦的血清測定IL-6及CRP含量,併對產婦的胎盤及胎膜採樣進行病理檢查.結果 (1)PROM閤併CMA者,母血IL-6、CRP含量明顯升高(P＜0.01).(2)隨著破膜時間的延長,母血IL-6及CRP的水平明顯升高(P＜0.01).(3)母血IL-6≥11 ng/L、CRP≥10 mg/L為預測診斷PROM閤併早期CMA的暘性率高.結論 母血IL-6及CRP水平的鑑測對PROM閤併CMA有一定的早期診斷意義.
목적 탐토검측모혈백세포개소-6(IL-6)급C반응단백(CRP)대인태막조파(PROM)이도치적융모막양막염(CMA)조기예측적의의.방법 채집태막조파잉부적혈청측정IL-6급CRP함량,병대산부적태반급태막채양진행병리검사.결과 (1)PROM합병CMA자,모혈IL-6、CRP함량명현승고(P＜0.01).(2)수착파막시간적연장,모혈IL-6급CRP적수평명현승고(P＜0.01).(3)모혈IL-6≥11 ng/L、CRP≥10 mg/L위예측진단PROM합병조기CMA적양성솔고.결론 모혈IL-6급CRP수평적감측대PROM합병CMA유일정적조기진단의의.
Objective To investigate significance of interleukin-6 and C-reactive protein as a predictor of chorioamnionitis in patients with premature rupture of the membranes. Methods Maternal serum was collected for detection of IL-6 and CRP, and placenta and membranes sample for pathology examination. Results ( 1 ) The level of maternal serum CRP and IL-6 raised signficantly in patients with premature rupture of membranes complicated by chorioamnionitis(P ＜0.01). (2)The levels of maternal serum CRP and IL-6 also raised signficantly with the time prolongation of premature rupture of themembranes( P ＜ 0. 0l ). ( 3 ) The positive rate of the predict diagnosis of PROM with early CMA was promoted by the standard of CRP≥10 mg/L and IL-6≥11 ng/L. Conclusion The maternal serum CRP and IL-6 determination could be used for the prediction of early CMA.
