CAJ | 학술논문

从桦褐孔菌子实体得到的多糖粗提物(polysaccharides from Inonotus obliquus, PIO)具有清除·OH、抑制自发性和Fe2+-Cys诱导过氧化脂质生成和减轻肝线粒体肿胀的效果.通过实验推测其抗氧化的机制是通过清除·OH,抑制·OH导致的过氧化从而保护膜系统.
종화갈공균자실체득도적다당조제물(polysaccharides from Inonotus obliquus, PIO)구유청제·OH、억제자발성화Fe2+-Cys유도과양화지질생성화감경간선립체종창적효과.통과실험추측기항양화적궤제시통과청제·OH,억제·OH도치적과양화종이보호막계통.
A crude polysaccharide fraction (PIO) from fruit bodies of the medicinal mushroom, Inonotus obliquus, exhibited strong ·OH scavenging activity as measured by the salicylic acid method. PIO also inhibited endogenous and Fe2+-Cys-induced lipid peroxidation, and mitochondrial swelling induced by the Fe2+- vitamin C system. It is proposed that the underlying anti-oxidation mechanism involves the initial elimination of ·OH radicals, which in turn suppresses peroxidation and protects membrane systems.