CAJ | 학술논문

目的应用实时三维超声心动图技术探讨扩张型心肌病患者左心室节段心肌不同步化指数、节段射血分数与左室整体射血分数的关系.方法对27例正常人和24例扩张型心肌病不同步化患者(DCM)进行三维图像采集,将左室心肌划分为基底、中间、心尖三个节段,测量左室射血分数(LV-EF)、节段射血分数(REF)、三个节段到达最小收缩末期容积时间的标准差(Tmsv Sel-SD)和最大时间差(TmsvSel-DIF).结果 DCM组中间段的Tmsv Sel-SD、Tmsv Sel-DIF与中间段的REF呈线性负相关(r=-0.6921,-0.6384,P<0.01).DCM组三节段Tmsv Sel-SD、Tmsv Sel-DIF与LV-EF的多元回归方程中仅中间段的Tmsv Sel-SD、Tmsv Sel-DIF与LV-EF存在回归关系(β=-0.7836,-0.7801,P<0.01).DCM组三节段REF与LV-EF的多元回归方程中三节段REF与LV-EF均存在回归关系(β=0.2234,0.7506.0.1880,P<0.05),中间段REF对LV-EF的贡献最大.结论 DCM不同步化患者中间段的Tmsv Sel-SD、Tmsv Sel-DIF及REF是影响其左室收缩功能的重要因素.
목적 응용실시삼유초성심동도기술탐토확장형심기병환자좌심실절단심기불동보화지수、절단사혈분수여좌실정체사혈분수적관계.방법 대27례정상인화24례확장형심기병불동보화환자(DCM)진행삼유도상채집,장좌실심기화분위기저、중간、심첨삼개절단,측량좌실사혈분수(LV-EF)、절단사혈분수(REF)、삼개절단도체최소수축말기용적시간적표준차(Tmsv Sel-SD)화최대시간차(TmsvSel-DIF).결과 DCM조중간단적Tmsv Sel-SD、Tmsv Sel-DIF여중간단적REF정선성부상관(r=-0.6921,-0.6384,P<0.01).DCM조삼절단Tmsv Sel-SD、Tmsv Sel-DIF여LV-EF적다원회귀방정중부중간단적Tmsv Sel-SD、Tmsv Sel-DIF여LV-EF존재회귀관계(β=-0.7836,-0.7801,P<0.01).DCM조삼절단REF여LV-EF적다원회귀방정중삼절단REF여LV-EF균존재회귀관계(β=0.2234,0.7506.0.1880,P<0.05),중간단REF대LV-EF적공헌최대.결론 DCM불동보화환자중간단적Tmsv Sel-SD、Tmsv Sel-DIF급REF시영향기좌실수축공능적중요인소.
Objective To evaluate the relationship among segmental dyssynchrony indexes, reginal ejection frction(EF) and global EF of left ventricle(LV) in the patients with dilated cardiomyopathy. Methods Standard deviation(SD) and maximal difference (Dif) in the time to minimal systolic volume in user-selected LV segments (Tmsv SeI-SD, Tmsv SeI-DIF) of LV global EF (LV-EF), reginal ejection fraction (REF) were acquired by real-time three-dimensional echocardiography in 27 controls and 24 DCM dyssynehrony patients. Data were grouped separately for 3 levels of the basal, mid and apical segments. Results The values of Tmsv SeI-SD and Tmsv SeI-DIF were linearly negatively correlated with REF in mid segment of DCM (r =-0.6921,-0.6384, P<0.01). It existed exclusive linear regression between Tmsv Sel-SD,Tmsv SeI-DIF and LV-EF only in mid segment's dyssynchrony indexes among three segments(β= -0.7836, -0.7801, P<0.01). Each REF in three segments was linear regression relationship with LV-EF(β= 0.2234,0.7506,0.1880, P <0.05) especially in mid segment. Conclusions The Tmsv SeI-SD, Tmsv SeI-DIF and REF of mid segment are important factors to influence left ventricular function in the patients with dilated cardiomyopathy.