CAJ | 학술논문

　　目的：探析静脉滴注阿奇霉素致不良反应，寻找阿奇霉素不良反应发生的规律以及表现，在临床应用中注意观察，避免发生不良反应。方法：选择2010年10月～2011年12月来我科采用静脉滴注阿奇霉素的患者150例，随机分为治疗组患者75例，对照组患者75例，治疗组患者采用减慢速度滴入阿奇霉素，对照组患者采用标准速度滴入阿奇霉素。观察两组患者出现不良反应的情况。结果：通过观察，治疗组患者出现的胃肠道反应、局部反应的发生率明显低于对照组，差异具有统计学意义（P＜0.01），皮肤反应以及其他出现的不良反应的发生率无明显差异（P＞0.01）。结论：在临床使用阿奇霉素需要注意用量及滴入速度，以保证患者使用药物的安全性。
　　목적：탐석정맥적주아기매소치불량반응，심조아기매소불량반응발생적규률이급표현，재림상응용중주의관찰，피면발생불량반응。방법：선택2010년10월～2011년12월래아과채용정맥적주아기매소적환자150례，수궤분위치료조환자75례，대조조환자75례，치료조환자채용감만속도적입아기매소，대조조환자채용표준속도적입아기매소。관찰량조환자출현불량반응적정황。결과：통과관찰，치료조환자출현적위장도반응、국부반응적발생솔명현저우대조조，차이구유통계학의의（P＜0.01），피부반응이급기타출현적불량반응적발생솔무명현차이（P＞0.01）。결론：재림상사용아기매소수요주의용량급적입속도，이보증환자사용약물적안전성。
Objective:Analysis of intravenous infusion of azithromycin adverse reactions caused by looking for the law as well as performance of azithromycin adverse reactions in the clinical application observe, to avoid adverse reactions. Methods: October 2010 to December 2011, our department with intravenous infusion of azithromycin 150 patients were randomly divided into treatment group of 75 patients, 75 patients of the control group, the treatment group were treated with drops slow down Rue Qi neomycin in the control group were treated with standard Huai speed drops Rue Qi adriamycin. Observed in patients with adverse reactions. Results:Through observation, the treatment group patients with gastrointestinal reactions, local reactions were significantly lower than the control group, significant differences (P<0.01), no significant difference in the incidence of skin reactions and other adverse reactions(P>0.01). Conclusion:The clinical use of azithromycin need to pay attention to the amount of trickle-down speed, to ensure that patients with drug safety.