CAJ | 학술논문

目的:评价动脉途径给予尿激酶和罂粟碱结合微导丝、微导管机械碎栓对急性脑血管闭塞的临床效果及安全性.方法:总结近5个月来治疗的急性脑血管闭塞,并给予尿激酶和罂粟碱结合微导丝、微导管机械碎栓治疗的8例病例资料进行回顾性分析总结.结果:治疗后8例中,闭塞血管即刻全部开通.术后1 d、1周、2周临床症状明显改善,NIHSS、ADL评分改善(P<0.01),1例术后第5天死于中枢性呼吸衰竭.结论:对时间窗内的急性脑血管闭塞患者,微导管、微导丝机械性碎栓结合动脉内注射尿激酶、罂粟碱治疗是安全有效的.
목적:평개동맥도경급여뇨격매화앵속감결합미도사、미도관궤계쇄전대급성뇌혈관폐새적림상효과급안전성.방법:총결근5개월래치료적급성뇌혈관폐새,병급여뇨격매화앵속감결합미도사、미도관궤계쇄전치료적8례병례자료진행회고성분석총결.결과:치료후8례중,폐새혈관즉각전부개통.술후1 d、1주、2주림상증상명현개선,NIHSS、ADL평분개선(P<0.01),1례술후제5천사우중추성호흡쇠갈.결론:대시간창내적급성뇌혈관폐새환자,미도관、미도사궤계성쇄전결합동맥내주사뇨격매、앵속감치료시안전유효적.
Objective: To analysis the clinical result and safety of treating acute cerebral artery occlusion with superselectire intracranial arterial thrombolysis by urokinase and papaverine and mechanical fragmentation by microcatheter and micro-guid wire. Methods: 8 patients of acute cerebral artery occlusion were treated by superselective intracranial arterial thrombolysis and mechanical fragmentation near five months. Results: Main thrombotic arteries in 8 cases were all recanal izated, the clinical symptoms were improved after therapy, the scals after 1 hour, 1 week and 2 week of the NIHSS and ADL were progresser than that of the before therapy. 1 case's symptom and signs with cerebral artery stenosis was progressed after therapy, but dead after 5 days for central respiratory failure after therapy. Conclusion: Superselective intracranial arterial thrombolysis by urokinase and papaverine and mechanical fragmentation by microcatheter and micro-guide wire in patients to acute cerebral artery occlusion is a safe and an effective and interventional therapy within the right time.