中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2012年
7期
722-725
,共4页
郭永豪%范军星%王哲%孙定勇%王海峰%李梦雷%刘佳%崔卫国%刘国华%郭万申
郭永豪%範軍星%王哲%孫定勇%王海峰%李夢雷%劉佳%崔衛國%劉國華%郭萬申
곽영호%범군성%왕철%손정용%왕해봉%리몽뢰%류가%최위국%류국화%곽만신
丙型肝炎%疫情%风险因素
丙型肝炎%疫情%風險因素
병형간염%역정%풍험인소
Hepatitis C%Epidemic%Risk factors
目的 调查2011年河南省某地一起丙型肝炎(丙肝)疫情的传染源及丙肝病毒(HCV)感染率.方法 在疫情地区选取不同方位的5个村庄,共计5187名居民作为调查对象,通过问卷调查个人信息,每名对象抽取5 ml血样检测抗-HCV,阳性者再采用Real-time PCR检测病毒核酸.结果 5187名调查对象年龄1～97岁,平均48岁,男女比例为1∶1.34.抗-HCV检测显示,HCV感染率平均为2.27％,其中1～9岁人群最低(1.55％),≥50岁年龄组最高(4.93％)；各村之间感染率差异显著(0.55％～8.68％).风险因素分析和距离与感染率线性回归分析表明,该次疫情可能与某诊所行医有相关性；多因素分析表明疫情主要传播途径为静脉注射、静脉滴注和内窥镜手术3种途径.结论 该次HCV感染疫情为医源性感染.
目的 調查2011年河南省某地一起丙型肝炎(丙肝)疫情的傳染源及丙肝病毒(HCV)感染率.方法 在疫情地區選取不同方位的5箇村莊,共計5187名居民作為調查對象,通過問捲調查箇人信息,每名對象抽取5 ml血樣檢測抗-HCV,暘性者再採用Real-time PCR檢測病毒覈痠.結果 5187名調查對象年齡1～97歲,平均48歲,男女比例為1∶1.34.抗-HCV檢測顯示,HCV感染率平均為2.27％,其中1～9歲人群最低(1.55％),≥50歲年齡組最高(4.93％)；各村之間感染率差異顯著(0.55％～8.68％).風險因素分析和距離與感染率線性迴歸分析錶明,該次疫情可能與某診所行醫有相關性；多因素分析錶明疫情主要傳播途徑為靜脈註射、靜脈滴註和內窺鏡手術3種途徑.結論 該次HCV感染疫情為醫源性感染.
목적 조사2011년하남성모지일기병형간염(병간)역정적전염원급병간병독(HCV)감염솔.방법 재역정지구선취불동방위적5개촌장,공계5187명거민작위조사대상,통과문권조사개인신식,매명대상추취5 ml혈양검측항-HCV,양성자재채용Real-time PCR검측병독핵산.결과 5187명조사대상년령1～97세,평균48세,남녀비례위1∶1.34.항-HCV검측현시,HCV감염솔평균위2.27％,기중1～9세인군최저(1.55％),≥50세년령조최고(4.93％)；각촌지간감염솔차이현저(0.55％～8.68％).풍험인소분석화거리여감염솔선성회귀분석표명,해차역정가능여모진소행의유상관성；다인소분석표명역정주요전파도경위정맥주사、정맥적주화내규경수술3충도경.결론 해차HCV감염역정위의원성감염.
Objective To describe the prevalence and risk factors of hepatitis C virus (HCV) occurred in Henan province,at the end of 2011.Methods Five villages round Maqiao township,including 5187 residents,were selected for the study.Five-milliliter-blood was drawn from every one of the interviewee.Clinical data including age,gender and anti-HCV antibody was recorded.Patients with positive antibodies against HCV were tested for HCV RNA.Results A total number of 5187 people from five villages were studied,with age span from 1 to 97.The average age was 48 years and the sex ratio was 1 ∶ 1.34.The anti-HCV result showed that the prevalence was 2.27％,with 1-9 age group the lowest ( 1.55％ ) and the ≥50 year-olds the highest (4.93％).Different villages seemed to have significant differences on the prevalence of HCV,with the highest as 8.68％ and the lowest as 0.55％.Under risk factors analysis and distance-infection rates linear regression analysis,data showed that the prevalence might have correlated to the behavior of a certain family-run clinic.Results from multivariate analysis indicated that factors as intravenous dropping,intravenous injection and the use of surgery/endoscope were associated with the HCV infection in this village.Conclusion Although the public health care system had been developed for more than ten years,iatrogenic infection was yet responsible for the infection of HCV patients in the rural areas of China that called for further attention paid to the system.
