中华急诊医学杂志
中華急診醫學雜誌
중화급진의학잡지
CHINESE JOURNAL OF EMERGENCY MEDICINE
2011年
2期
156-159
,共4页
李小彦%王小波%刘秀峰%李树贵
李小彥%王小波%劉秀峰%李樹貴
리소언%왕소파%류수봉%리수귀
重症急性胰腺炎%器官功能衰竭%患病率%危险因素%年龄%并存病%APACHE评分%胰腺坏死%腹腔间隔室综合征
重癥急性胰腺炎%器官功能衰竭%患病率%危險因素%年齡%併存病%APACHE評分%胰腺壞死%腹腔間隔室綜閤徵
중증급성이선염%기관공능쇠갈%환병솔%위험인소%년령%병존병%APACHE평분%이선배사%복강간격실종합정
Severe acute pancreatitis%Organ failure%Prevalence%Risk factor%Age%Comorbidit%APACHE Score%Pancreatic necrosis%Abdominal compartment syndrome
目的 调查重症急性胰腺炎(SAP)患者器官功能衰竭的患病率,分析其发病的危险因素.方法 回顾性分析2000年3月至2009年10月于山西省晋中市第一人民医院ICU住院的186例SAP患者.SAP诊断依据2006年中华医学会外科学会制订的重症急性胰腺炎诊断标准.收集年龄、性别、病因、并存病、APACHE Ⅱ评分、CECT胰腺坏死程度、CT严重性指数(CTSI)、腹腔间隔窒综合征(ACS)、器官功能衰竭数目与死亡人数等资料.计算器官功能衰竭的患病率和病死率.采用非条件多因素Logistic回归分析方法确定器官功能衰竭的危险因素.结果 186例SAP患者中,96例患器官功能衰竭.96例SAP器官功能衰竭患者中,47例死亡.SAP患者器官功能衰竭患病率与年龄、并存病数目、APACHEⅡ评分、CECT胰腺坏死程度、CTSI和ACS显著相关.器官功能衰竭数目随着年龄、并存病数目、APACHEⅡ评分,CECT胰腺坏死程度增加显著增加.进入非条件多因素Logistic回归方程的因素有年龄、并存病数目、APACHEⅡ评分、CECT胰腺坏死程度、CTSI和ACS.结论 SAP患者器官功能衰竭的患病率为51.6%,与之相关的病死率为49.0%,年龄、并存病数目、APACHEⅡ评分、CECT胰腺坏死程度、CTSI和ACS是SAP患者器官功能衰竭的独立危险因素.
目的 調查重癥急性胰腺炎(SAP)患者器官功能衰竭的患病率,分析其髮病的危險因素.方法 迴顧性分析2000年3月至2009年10月于山西省晉中市第一人民醫院ICU住院的186例SAP患者.SAP診斷依據2006年中華醫學會外科學會製訂的重癥急性胰腺炎診斷標準.收集年齡、性彆、病因、併存病、APACHE Ⅱ評分、CECT胰腺壞死程度、CT嚴重性指數(CTSI)、腹腔間隔窒綜閤徵(ACS)、器官功能衰竭數目與死亡人數等資料.計算器官功能衰竭的患病率和病死率.採用非條件多因素Logistic迴歸分析方法確定器官功能衰竭的危險因素.結果 186例SAP患者中,96例患器官功能衰竭.96例SAP器官功能衰竭患者中,47例死亡.SAP患者器官功能衰竭患病率與年齡、併存病數目、APACHEⅡ評分、CECT胰腺壞死程度、CTSI和ACS顯著相關.器官功能衰竭數目隨著年齡、併存病數目、APACHEⅡ評分,CECT胰腺壞死程度增加顯著增加.進入非條件多因素Logistic迴歸方程的因素有年齡、併存病數目、APACHEⅡ評分、CECT胰腺壞死程度、CTSI和ACS.結論 SAP患者器官功能衰竭的患病率為51.6%,與之相關的病死率為49.0%,年齡、併存病數目、APACHEⅡ評分、CECT胰腺壞死程度、CTSI和ACS是SAP患者器官功能衰竭的獨立危險因素.
목적 조사중증급성이선염(SAP)환자기관공능쇠갈적환병솔,분석기발병적위험인소.방법 회고성분석2000년3월지2009년10월우산서성진중시제일인민의원ICU주원적186례SAP환자.SAP진단의거2006년중화의학회외과학회제정적중증급성이선염진단표준.수집년령、성별、병인、병존병、APACHE Ⅱ평분、CECT이선배사정도、CT엄중성지수(CTSI)、복강간격질종합정(ACS)、기관공능쇠갈수목여사망인수등자료.계산기관공능쇠갈적환병솔화병사솔.채용비조건다인소Logistic회귀분석방법학정기관공능쇠갈적위험인소.결과 186례SAP환자중,96례환기관공능쇠갈.96례SAP기관공능쇠갈환자중,47례사망.SAP환자기관공능쇠갈환병솔여년령、병존병수목、APACHEⅡ평분、CECT이선배사정도、CTSI화ACS현저상관.기관공능쇠갈수목수착년령、병존병수목、APACHEⅡ평분,CECT이선배사정도증가현저증가.진입비조건다인소Logistic회귀방정적인소유년령、병존병수목、APACHEⅡ평분、CECT이선배사정도、CTSI화ACS.결론 SAP환자기관공능쇠갈적환병솔위51.6%,여지상관적병사솔위49.0%,년령、병존병수목、APACHEⅡ평분、CECT이선배사정도、CTSI화ACS시SAP환자기관공능쇠갈적독립위험인소.
Objective To determine the prevalence of organ failure and its risk factors in patients with severe acute pancreatitis(SAP). Method A retrospective analysis was conducted in 186 patients, who were hospitalized in the intensive care unit of Jinzhong First People's Hospital with SAP between March 2000and October 2009. SAP patients met the diagnostic criteria of SAP set by Surgery Society of Chinese Medical Association in 2006. The variables included age, gender, etiology of SAP, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis, CT Severity Index ( CTSI ), abdomen compartment syndrome (ACS) ,the number of organ failure and the number of death. The prevalence and mortality of organ failure were calculated. The above-mentioned variables were analyzed by unconditional multivariate logistic regression analysis to determine the independent risk factors for organ failure in SAP. Results Of 186 patients, 96had organ failure. In 96 patients with organ failure, 47 died. There was a significant association between the prevalence of organ failure and age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis, CTSI, ACS. An increase in age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis correlated with an increase in the number of organ failure. Age, the number of comorbidit, APACHE Ⅱ score,CECT pancreatic necrosis, CTSI and ACS went into the unconditional multivariate logistic regression equation. Conclusions Organ failure occurred in 51.6% of 186 patients with SAP. The mortality of SAP with organ failure is 49.0%. Age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis,CTSI and ACS are independent risk factors of organ failure.
