CAJ | 학술논문

目的总结联合用药组成的同步序贯治疗在预防绒毛膜癌化疗不良反应中的护理要点.方法对65例接受同步序贯治疗的绒毛膜癌患者给予造血功能障碍、消化道反应、肝肾功能损伤的相应护理及心理护理.结果经同步序贯治疗的65例患者中,近期治愈45例,临床好转9例,总有效率为83.1％,平均用药3～4个疗程.经过第一疗程治疗后出现造血功能障碍11例,5例发生不同程度的食欲减退、恶心、呕吐和口腔溃疡,肾功能损害2例,脱发3例,静脉注射处色素沉着5例.对症治疗后不良反应均消除.结论针对绒毛膜癌化疗患者在化疗期间可能出现的不良反应进行同步序贯治疗并给予精心的护理是保证肿瘤患者顺利、高效地完成化疗及治疗疾病的重要环节.
목적 총결연합용약조성적동보서관치료재예방융모막암화료불량반응중적호리요점.방법 대65례접수동보서관치료적융모막암환자급여조혈공능장애、소화도반응、간신공능손상적상응호리급심리호리.결과 경동보서관치료적65례환자중,근기치유45례,림상호전9례,총유효솔위83.1％,평균용약3～4개료정.경과제일료정치료후출현조혈공능장애11례,5례발생불동정도적식욕감퇴、악심、구토화구강궤양,신공능손해2례,탈발3례,정맥주사처색소침착5례.대증치료후불량반응균소제.결론 침대융모막암화료환자재화료기간가능출현적불량반응진행동보서관치료병급여정심적호리시보증종류환자순리、고효지완성화료급치료질병적중요배절.
Objective To summarize nursing points in the synchronous and sequential chemotherapy composed of combination medications to prevent adverse reactions of choriocarcinoma treatment.Methods 65 patients with choriocarcinoma who had received synchronous sequential chemotherapy were given nursing and physiological nursing concerning hematopoietic dysfunction,gastrointestinal reaction as well as liver and kidney dysfunction.Results Out of the 65 patients who had received synchronous sequential chemotherapy,45 were cured and 9 had clinical improvements,with total effective rate of 83.1％ and 3-4 medication courses on average.After the first treatment course,11 patients had hematopoietic dysfunction,5 had decreased food appetite,nausea,vomiting and oral cavity ulcer of different degrees,2 had kidney dysfunction,3 had alopecia and 5 had pigmentation where they received intravenous injection.But all adverse reactions disappeared after symptomatic treatment.Conclusions Synchronous sequential chemotherapy as well as careful nursing is very important to cure adverse reactions in choriocarcinoma patients with chemotherapy.