中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2012年
10期
888-891
,共4页
唐晓燕%康锴%尚思远%徐超%李幸乐%马红霞%陈豪敏%许汴利
唐曉燕%康鍇%尚思遠%徐超%李倖樂%馬紅霞%陳豪敏%許汴利
당효연%강개%상사원%서초%리행악%마홍하%진호민%허변리
脑炎病毒,日本%流行病学%病毒抗体
腦炎病毒,日本%流行病學%病毒抗體
뇌염병독,일본%류행병학%병독항체
Encephalitis virus,Japanese%Epidemiology%Viral antibody
目的 了解2010年河南省流行性乙型脑炎(乙脑)流行特点及健康人群乙脑病毒抗体水平.方法 提取2010年河南省监测的433例乙脑患者资料,用描述流行病学方法对其进行分析.于2010年选取洛阳市和信阳市为调查点,采用整群分层抽样方法在两市各选择12个行政村(社区居委会),选择＜1、1～2、3～4、5～6、7～14、15 ～ 19、20 ～59和≥60岁8个年龄组健康人群作为调查对象,共519名.分别于2010年的5月和11月调查和采集同一人群血液标本,共1008份,用微量细胞中和试验检测乙脑病毒抗体.结果 2010年河南省乙脑发病率为0.46/10万(433/94 130 434).97.69％(423/433)的患者集中在7-9月；81.06％ (351/433)的患者分布在南阳、信阳、洛阳、驻马店和周口市.河南省0～14岁人群乙脑发病占82.22％( 356/433),≥15岁人群发病占17.78％(77/433).洛阳市≥15岁人群乙脑发病占65.79％( 50/76),明显高于河南省的17.78％(x2=79.57,P＜0.05).河南省乙脑发病以散居儿童为主,占58.89％(255/433),洛阳市以农民为主,占44.74％(34/76).洛阳市≥15岁健康人群乙脑抗体阳性率为48.94％(46/94),低于信阳市的97.78％( 88/90),差异有统计学意义(x2=55.42,P＜0.05).洛阳市健康人群中有免疫史者乙脑抗体阳性率为50.41％(61/121),高于无免疫史者的16.67％(6/36),差异有统计学意义(x2=12.92,P＜0.05).信阳市健康人群中有免疫史者乙脑抗体阳性率为67.11％(51/76),高于无免疫史者的46.39％(45/97),差异有统计学意义(x2=7.40,P＜0.05).结论 河南省乙脑发病呈季节性、地域性,不同年龄、职业人群发病有差异.河南省与洛阳市乙脑发病年龄和职业的差异与二者健康人群乙脑抗体水平的差异相一致.
目的 瞭解2010年河南省流行性乙型腦炎(乙腦)流行特點及健康人群乙腦病毒抗體水平.方法 提取2010年河南省鑑測的433例乙腦患者資料,用描述流行病學方法對其進行分析.于2010年選取洛暘市和信暘市為調查點,採用整群分層抽樣方法在兩市各選擇12箇行政村(社區居委會),選擇＜1、1～2、3～4、5～6、7～14、15 ～ 19、20 ～59和≥60歲8箇年齡組健康人群作為調查對象,共519名.分彆于2010年的5月和11月調查和採集同一人群血液標本,共1008份,用微量細胞中和試驗檢測乙腦病毒抗體.結果 2010年河南省乙腦髮病率為0.46/10萬(433/94 130 434).97.69％(423/433)的患者集中在7-9月；81.06％ (351/433)的患者分佈在南暘、信暘、洛暘、駐馬店和週口市.河南省0～14歲人群乙腦髮病佔82.22％( 356/433),≥15歲人群髮病佔17.78％(77/433).洛暘市≥15歲人群乙腦髮病佔65.79％( 50/76),明顯高于河南省的17.78％(x2=79.57,P＜0.05).河南省乙腦髮病以散居兒童為主,佔58.89％(255/433),洛暘市以農民為主,佔44.74％(34/76).洛暘市≥15歲健康人群乙腦抗體暘性率為48.94％(46/94),低于信暘市的97.78％( 88/90),差異有統計學意義(x2=55.42,P＜0.05).洛暘市健康人群中有免疫史者乙腦抗體暘性率為50.41％(61/121),高于無免疫史者的16.67％(6/36),差異有統計學意義(x2=12.92,P＜0.05).信暘市健康人群中有免疫史者乙腦抗體暘性率為67.11％(51/76),高于無免疫史者的46.39％(45/97),差異有統計學意義(x2=7.40,P＜0.05).結論 河南省乙腦髮病呈季節性、地域性,不同年齡、職業人群髮病有差異.河南省與洛暘市乙腦髮病年齡和職業的差異與二者健康人群乙腦抗體水平的差異相一緻.
목적 료해2010년하남성류행성을형뇌염(을뇌)류행특점급건강인군을뇌병독항체수평.방법 제취2010년하남성감측적433례을뇌환자자료,용묘술류행병학방법대기진행분석.우2010년선취락양시화신양시위조사점,채용정군분층추양방법재량시각선택12개행정촌(사구거위회),선택＜1、1～2、3～4、5～6、7～14、15 ～ 19、20 ～59화≥60세8개년령조건강인군작위조사대상,공519명.분별우2010년적5월화11월조사화채집동일인군혈액표본,공1008빈,용미량세포중화시험검측을뇌병독항체.결과 2010년하남성을뇌발병솔위0.46/10만(433/94 130 434).97.69％(423/433)적환자집중재7-9월；81.06％ (351/433)적환자분포재남양、신양、락양、주마점화주구시.하남성0～14세인군을뇌발병점82.22％( 356/433),≥15세인군발병점17.78％(77/433).락양시≥15세인군을뇌발병점65.79％( 50/76),명현고우하남성적17.78％(x2=79.57,P＜0.05).하남성을뇌발병이산거인동위주,점58.89％(255/433),락양시이농민위주,점44.74％(34/76).락양시≥15세건강인군을뇌항체양성솔위48.94％(46/94),저우신양시적97.78％( 88/90),차이유통계학의의(x2=55.42,P＜0.05).락양시건강인군중유면역사자을뇌항체양성솔위50.41％(61/121),고우무면역사자적16.67％(6/36),차이유통계학의의(x2=12.92,P＜0.05).신양시건강인군중유면역사자을뇌항체양성솔위67.11％(51/76),고우무면역사자적46.39％(45/97),차이유통계학의의(x2=7.40,P＜0.05).결론 하남성을뇌발병정계절성、지역성,불동년령、직업인군발병유차이.하남성여락양시을뇌발병년령화직업적차이여이자건강인군을뇌항체수평적차이상일치.
Objective To understand the epidemic characteristics and viral antibody level among healthy people of Japanese B encephalitis ( JE ) in Henan province in 2010.Methods A total of 433 selected JE cases in Henan province in 2010 were analyzed by descriptive epidemiological method.Xinyang and Luoyang were selected as survey sites in 2010.12 administrative villages were randomly selected from both cities.As the investigation objects,519 healthy people from the two cities were randomly selected by eight age groups:less than one year old,1 -2 years old,3 -4 years old,5 -6 years old,7 - 14 years old,15 - 19 years old,20 - 59 years old,and above 60 years old.A total of 1008 samples of blood specimens were collected both in May and November,and JE viral antibody was detected by microcytopathic effect neutralization test.Results The incidence rate of JE was 0.46/100 000 (433/94 130 434)in Henan province in 2010.97.69％ (423/433)of the patients were found between July and September,and 81.06％(351/433) were distributed in Nanyang,Xinyang,Luoyang,Zhumadian and Zhoukou city.Children aged 0 to 14 years were the primarily affected group (82.22％,356/433),the people above 15 years old accounted for 17.78％ (77/433) of whole cases in Henan province,but the same group accounted for 65.79％ (50/76) of whole cases in Luoyang city,which obviously higher than the percentage in Henan province(x2 =79.57,P ＜ 0.05 ).Most patients were scattered children in Henan province,accounting for 58.89％ (255/433).In Luoyang city,most patients were peasants,accounting for 44.74％ (34/76).The antibody positive rate of JE among health people above 15 years old in Luoyang city was 48.94％ (46/94),which was lower than it in Xinyang city at 97.78％ (88/90).The difference showed statistical significance (x2 =55.42,P ＜ 0.05 ).The antibody positive rate among healthy people under vaccination was 50.41％ (61/121),which was obviously higher than that among people without vaccination,at 16.67％ (6/36) in Luoyang city.The difference showed statistical significance (x2 =12.92,P ＜ 0.05 ).The antibody positive rate among healthy people under vaccination was 67.11％ (51/76)in Xinyang city,which was obviously higher than that among people without vaccination,at 46.39％ (45/97).The difference showed statistical significance (x2=7.40,P ＜ 0.05 ).Conclusion The incidence of JE showed seasonal and regional characteristics,there were differences among ages and occupations.The difference was consistent with the difference in viral antibody level among health people in Henan province and Luoyang city.
