中华神经外科杂志
中華神經外科雜誌
중화신경외과잡지
Chinese Journal of Neurosurgery
2008年
5期
327-330
,共4页
徐波涛%梁军潮%吴鸿勋%覃子衡%王玉宝%王国良%宁琼芳%王伟民
徐波濤%樑軍潮%吳鴻勛%覃子衡%王玉寶%王國良%寧瓊芳%王偉民
서파도%량군조%오홍훈%담자형%왕옥보%왕국량%저경방%왕위민
立体定位技术%放射外科手术%垂体肿瘤%伽玛刀%远期疗效
立體定位技術%放射外科手術%垂體腫瘤%伽瑪刀%遠期療效
입체정위기술%방사외과수술%수체종류%가마도%원기료효
Stereotactic techniques%Radiosurgery%Pituitary neoplasms%Gamma knife%Prostecdtive efficacy
目的 分析伽玛刀治疗垂体微腺瘤的远期疗效.方法 回顾性分析Leksell伽玛刀治疗的109例垂体微腺瘤.结果 影像学肿瘤消失、缩小、无变化和增大分别为45例、37例、22例和5例;血液激素完全恢复39例,部分恢复23例,无明显变化15例,继续增高14例.33例垂体功能低下的患者,治疗后28例恢复正常;8例目前存在垂体激素水平低下,但只有1例与本次治疗有明确关系,5例无自诉症状,需要激素替代治疗有3例.症状完全消失或明显改善62.6%,稍改善或无变化31.3%,继续恶化6.1%.结论 伽玛刀治疗效果肯定,创伤小,治疗风险低,可以作为治疗垂体微腺瘤的主要方法之一.
目的 分析伽瑪刀治療垂體微腺瘤的遠期療效.方法 迴顧性分析Leksell伽瑪刀治療的109例垂體微腺瘤.結果 影像學腫瘤消失、縮小、無變化和增大分彆為45例、37例、22例和5例;血液激素完全恢複39例,部分恢複23例,無明顯變化15例,繼續增高14例.33例垂體功能低下的患者,治療後28例恢複正常;8例目前存在垂體激素水平低下,但隻有1例與本次治療有明確關繫,5例無自訴癥狀,需要激素替代治療有3例.癥狀完全消失或明顯改善62.6%,稍改善或無變化31.3%,繼續噁化6.1%.結論 伽瑪刀治療效果肯定,創傷小,治療風險低,可以作為治療垂體微腺瘤的主要方法之一.
목적 분석가마도치료수체미선류적원기료효.방법 회고성분석Leksell가마도치료적109례수체미선류.결과 영상학종류소실、축소、무변화화증대분별위45례、37례、22례화5례;혈액격소완전회복39례,부분회복23례,무명현변화15례,계속증고14례.33례수체공능저하적환자,치료후28례회복정상;8례목전존재수체격소수평저하,단지유1례여본차치료유명학관계,5례무자소증상,수요격소체대치료유3례.증상완전소실혹명현개선62.6%,초개선혹무변화31.3%,계속악화6.1%.결론 가마도치료효과긍정,창상소,치료풍험저,가이작위치료수체미선류적주요방법지일.
Objective To evaluate long-term efficacy of gamma knife on the treatment of pituitary microadenoma.Method We followed up all the patients of pituitary microadenoma performed with Leksell gamma knife in our unit during 1995.8-1998.12,in whom 109 cases were obtained which information fitting our demand.Results In the imaging follow-up,the number of vanishing,diminution,unchanging and augmentation of tumor volume was in 45、37、22 and 5 cases respectively.In the endocrine follow-up,the number of complete recovery of hormone was in 39 cases,partly recovery in 23 cases,no marked change in 15 cases,and keeping on rising in 14 cases.In our group,33 cases suffered from hypopituitarism before gamma knife,among which 28 cases recovered normally after radiosurgery,achieving effective percentage of 84.8%.There were 8 cases showing some hypophyseal hormone lower than normal level in the present blood examination,among them,however,only one was perhaps related to the gamma knife treatment,and 5 oases had no complaints,and the other 3 displayed symptom and needed hormone replacement therapy,occupying percentage of 2.7%.Patients whose complaints disappeared completely or obviously accounted for 62.6%.showed slight or no improvement for 31.3%.and aggravated for 6.1%.Conclusions Gamma knife treatment for pituitary microadenoma showes affirmative efficacy,brings little trauma,has lower risk and less complication.It could be one choice of surgical therapeutic method for pituitary microadenoma.
