中华消化外科杂志
中華消化外科雜誌
중화소화외과잡지
CHINESE JOURNAL OF DIGESTIVE SURGERY
2009年
1期
24-26
,共3页
李心翔%郑成竹%Raul J.Rosenthal
李心翔%鄭成竹%Raul J.Rosenthal
리심상%정성죽%Raul J.Rosenthal
肥胖症%病态%吻合术%Roux-en-Y%腹腔镜检查%糖尿病%2型
肥胖癥%病態%吻閤術%Roux-en-Y%腹腔鏡檢查%糖尿病%2型
비반증%병태%문합술%Roux-en-Y%복강경검사%당뇨병%2형
Obesity,morbid%Anastomosis,Roux-en-Y%Laparoscopy%Diabetes mellitus,type 2
目的 评价腹腔镜Roux-en-Y胃分流术(LRYGB)对病态性肥胖合并2型糖尿病患者的治疗效果,探讨该术式治疗糖尿病的可能机制.方法 前瞻性分析2007年1月至7月美国克利夫兰医院30例体质量指数(BMI)≥35.00合并2型糖尿病的病态性肥胖患者的临床资料,采用t检验分析患者接受LRYGB后的疗效.结果 与术前比较,术后第6个月的BMI、空腹血糖、糖化血红蛋白明显降低(t=27.399,23.025,15.593,P＜0.05).第2个月治愈率为70%(21/30),第6个月治愈率为90%(27/30),3例糖尿病症状得到改善.进一步分析术后第2个月和第6个月体质量下降程度,改善患者分别为27.89%±5.51%、45.73%±2.82%,治愈患者分别为35.65%±1.97%、58.00%±1.05%,糖尿病治愈患者比改善患者下降幅度大(t=5.755,7.081,P＜0.05).结论 LRYGB对病态性肥胖合并2型糖尿病患者有着良好治疗效果,体质量下降幅度越大,糖尿病治愈可能性就越大.
目的 評價腹腔鏡Roux-en-Y胃分流術(LRYGB)對病態性肥胖閤併2型糖尿病患者的治療效果,探討該術式治療糖尿病的可能機製.方法 前瞻性分析2007年1月至7月美國剋利伕蘭醫院30例體質量指數(BMI)≥35.00閤併2型糖尿病的病態性肥胖患者的臨床資料,採用t檢驗分析患者接受LRYGB後的療效.結果 與術前比較,術後第6箇月的BMI、空腹血糖、糖化血紅蛋白明顯降低(t=27.399,23.025,15.593,P＜0.05).第2箇月治愈率為70%(21/30),第6箇月治愈率為90%(27/30),3例糖尿病癥狀得到改善.進一步分析術後第2箇月和第6箇月體質量下降程度,改善患者分彆為27.89%±5.51%、45.73%±2.82%,治愈患者分彆為35.65%±1.97%、58.00%±1.05%,糖尿病治愈患者比改善患者下降幅度大(t=5.755,7.081,P＜0.05).結論 LRYGB對病態性肥胖閤併2型糖尿病患者有著良好治療效果,體質量下降幅度越大,糖尿病治愈可能性就越大.
목적 평개복강경Roux-en-Y위분류술(LRYGB)대병태성비반합병2형당뇨병환자적치료효과,탐토해술식치료당뇨병적가능궤제.방법 전첨성분석2007년1월지7월미국극리부란의원30례체질량지수(BMI)≥35.00합병2형당뇨병적병태성비반환자적림상자료,채용t검험분석환자접수LRYGB후적료효.결과 여술전비교,술후제6개월적BMI、공복혈당、당화혈홍단백명현강저(t=27.399,23.025,15.593,P＜0.05).제2개월치유솔위70%(21/30),제6개월치유솔위90%(27/30),3례당뇨병증상득도개선.진일보분석술후제2개월화제6개월체질량하강정도,개선환자분별위27.89%±5.51%、45.73%±2.82%,치유환자분별위35.65%±1.97%、58.00%±1.05%,당뇨병치유환자비개선환자하강폭도대(t=5.755,7.081,P＜0.05).결론 LRYGB대병태성비반합병2형당뇨병환자유착량호치료효과,체질량하강폭도월대,당뇨병치유가능성취월대.
Objective To evaluate the efficacy of laparoscopic Roux-en-Y gastric bypass(LRYGB)in the treatment of morbid obesity complicated with type 2 diabetes mellitus,and to discuss the mechanism of LRYGB in the treatment of type 2 diabetes mellitus.Methods The clinical data of 30 type 2 diabetes mellitus patients with body mass index(BMI)≥35.00 who had undergone LRYGB from January 2007 to July 2007 in Cleveland Clinic were prospectively analyzed.The pre-and postoperative clinical parameters wcl"e analyzed by t test.Results The BMI,fasting plasma glucose and glycosylated hemoglobin were significantly decreased 6 months after the operation(t=27.399,23.025.15.593,P＜0.05).The cure rate at the end ofthe second month was 70%(21/30),and it was increased to 90%at the end of sixth month(27/30).The condition of the remaining 3 patients were improved.At the end of the second and sixth month',ffter operation,the BMIs of the patients who were cured by LRYGB were decreased by 27.89%±5.51%and 45.73%±2.82%.and the BMIs of the patients whose condition was improved were decreased by 35.65%±1.97%and 58.00%±3.05%(t=5.755,7.081,P＜0.05).Conclusions LRYGB is effective in the treatment of morbid obesity complicated with type 2 diabetes mellitus.The curability of morbid obesity increases as the BMI decreases.
