CAJ | 학술논문

采用反相高效液相色谱法测定25例2型糖尿病患者和25例健康对照者空腹血清游离脂肪酸(FFA)的主要成分,并比较吡格列酮治疗前、治疗后3个月和1年FFA各成分水平的改变,发现2型糖尿病患者血清中月桂酸、豆蔻酸和硬脂酸的水平比对照组明显升高,吡格列酮治疗可以降低2型糖尿病患者上述脂肪酸的水平.
채용반상고효액상색보법측정25례2형당뇨병환자화25례건강대조자공복혈청유리지방산(FFA)적주요성분,병비교필격렬동치료전、치료후3개월화1년FFA각성분수평적개변,발현2형당뇨병환자혈청중월계산、두구산화경지산적수평비대조조명현승고,필격렬동치료가이강저2형당뇨병환자상술지방산적수평.
Components of free fatty acids (FFA) were examined by reverse high performance liquid chromatography in 25 patients with type 2 diabetes and 25 control subjects.The changes in components of FFA were observed before treatment, at 3 months and 1 year after treatment with pioglitazone in type 2 diabetic patients.The serum lauric acid, myristic acid and stearic acid levels were much higher in the diabetic patients than those in control subjects.Pioglitazone could decrease the levels of these fatty acids in the patients with type 2 diabetes mellitus.