CAJ | 학술논문

目的观察胺碘酮联合贝那普利对阵发性房颤的疗效.方法选择我院2008年3月至2010年3月期间阵发性心房纤颤患者145例,随机分为治疗组(胺碘酮+贝那普利)和对照组(单用胺碘酮),对照组应用胺碘酮治疗,治疗组在此基础加用贝那普利.结果随访12个月,治疗组窦性心律维持率明显高于对照组(P＜0.05),左房内径亦有显著性缩小(P＜0.05).结论贝那普利具有抑制心房电重构和解剖重构,降低房颤复发率及阻止房颤持续的作用,胺碘酮联合贝那普利能更有效地治疗和预防阵发性房颤.
목적 관찰알전동연합패나보리대진발성방전적료효.방법 선택아원2008년3월지2010년3월기간진발성심방섬전환자145례,수궤분위치료조(알전동+패나보리)화대조조(단용알전동),대조조응용알전동치료,치료조재차기출가용패나보리.결과 수방12개월,치료조두성심률유지솔명현고우대조조(P＜0.05),좌방내경역유현저성축소(P＜0.05).결론 패나보리구유억제심방전중구화해부중구,강저방전복발솔급조지방전지속적작용,알전동연합패나보리능경유효지치료화예방진발성방전.
Objective To observe the effect of Amiodarone combined with Benazepril treating paroxysmal atrial fibrillation.Methods 145 Paroxysmal atrial fibrillation patients were enrolled and randomly divided into treatment group and control group.The treatment group were treated with Amiodarone and Benazepril,and the control group only with Amiodarone.All the patients have been observed for 12 months.Results The sinus rhythm maintenace rate in treatment group is higher than control group and the left ateial diameter decreased remarkably in treated group than that in control group (P ＜ 0.05).Conclusion Benazepril can inhibit electronic and anatomical remodeling of atrial,and can reduce the recurrence rate of atrial fibrillation,and prevent persistence of atrial fibrillation.So Amiodarone combined with Benazepril can more effectively to treat and prevent the patients with paroxysmal atrial fibrillation