中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
9期
106-107
,共2页
二甲双胍%代谢综合征%2型糖尿病%代谢指数
二甲雙胍%代謝綜閤徵%2型糖尿病%代謝指數
이갑쌍고%대사종합정%2형당뇨병%대사지수
Metformin%Type 2 diabetes mellitus%Metabolic syndrom%Metabolic indices
目的 观察二甲双胍对合并代谢综合征的2型糖尿病患者代谢指数的影响.方法 将45例正使用诺和灵30R治疗的合并代谢综合征的2型糖尿病患者随机分为两组,对照组维持原治疗方案,治疗组加用二甲双胍(0.5 g 3次/d)观察随访12周.结果 治疗组与联合二甲双胍治疗前相比,联合二甲双胍治疗后空腹血糖,糖化血红蛋白(HbAlc),甘油三酯(TG),总胆固醇(TC),体质指数(BMI),腰围(WC)明显下降(P＜0.001).血压无明显改变.对照组的上述指标与治疗前相比差异无统计学意义(P＞0.05).结论 对合并代谢综合征的2型糖尿病患者联合应用二甲双胍可有效控制血糖、血脂,减轻体重.
目的 觀察二甲雙胍對閤併代謝綜閤徵的2型糖尿病患者代謝指數的影響.方法 將45例正使用諾和靈30R治療的閤併代謝綜閤徵的2型糖尿病患者隨機分為兩組,對照組維持原治療方案,治療組加用二甲雙胍(0.5 g 3次/d)觀察隨訪12週.結果 治療組與聯閤二甲雙胍治療前相比,聯閤二甲雙胍治療後空腹血糖,糖化血紅蛋白(HbAlc),甘油三酯(TG),總膽固醇(TC),體質指數(BMI),腰圍(WC)明顯下降(P＜0.001).血壓無明顯改變.對照組的上述指標與治療前相比差異無統計學意義(P＞0.05).結論 對閤併代謝綜閤徵的2型糖尿病患者聯閤應用二甲雙胍可有效控製血糖、血脂,減輕體重.
목적 관찰이갑쌍고대합병대사종합정적2형당뇨병환자대사지수적영향.방법 장45례정사용낙화령30R치료적합병대사종합정적2형당뇨병환자수궤분위량조,대조조유지원치료방안,치료조가용이갑쌍고(0.5 g 3차/d)관찰수방12주.결과 치료조여연합이갑쌍고치료전상비,연합이갑쌍고치료후공복혈당,당화혈홍단백(HbAlc),감유삼지(TG),총담고순(TC),체질지수(BMI),요위(WC)명현하강(P＜0.001).혈압무명현개변.대조조적상술지표여치료전상비차이무통계학의의(P＞0.05).결론 대합병대사종합정적2형당뇨병환자연합응용이갑쌍고가유효공제혈당、혈지,감경체중.
Objective To study the effects of metformin on metabolic indices in type 2 diabetic mellitus patients with metabolic syndrome.Methods 45 type 2 diabetes patients with metabolic syndrome who were using insulin Novolin 30R were grouped randomly by metformin (1.5 g daily) combined with insulin Novolin 30R (n =24) ,insulin Novolin 30R (n = 21) for 12 weeks.The metabolic indices of FPG,HbAlc,TG,TC,BMI,WC before and after treatment were observed.Results There were statistically significant difference in FPG,HbAlc,TG,TC,BMI,WC before and after treatment in metformin combined with insulin Novolin 30R group (P ＜ 0.001) compared with the use of only insulin Novolin 30R group (P ＞ 0.05).And there were no statistically significant difference in blood pressure in two groups.Conclusion Metformin has beneficial effects in effectively controlling blood glucose,blood lipids and weight loss in type 2 diabetic mellitus patients with metabolic syndrome.
