国际移植与血液净化杂志
國際移植與血液淨化雜誌
국제이식여혈액정화잡지
INTERNATIONAL JOURNAL OF TRANSPLANTATION AND HEMOPURIFICATION
2012年
4期
33-35
,共3页
罗明乾%冼翠华%石晓峰%钟业娟%轩慧杰
囉明乾%冼翠華%石曉峰%鐘業娟%軒慧傑
라명건%승취화%석효봉%종업연%헌혜걸
百草枯%中毒%预后%预防
百草枯%中毒%預後%預防
백초고%중독%예후%예방
Paraquat%Poisoning%Prognosis%Prevention
目的 探讨急性百草枯中毒患者的临床特点,以寻找降低病死率的对策.方法 对我院2008年1月至2012年1月收治的14例重度急性百草枯中毒患者的临床表现和治疗方法进行回顾性分析.结果 14例患者中死亡9例,病死率高达64%,7例死于医院,中毒至死亡时间为40~175 h,2例放弃治疗出院后死亡,死亡原因均为多脏器功能衰竭.存活患者5例,均及时给予催吐、洗胃和导泻等治疗和支持治疗,4例患者表现为非少尿型急性肾功能衰竭.结论 急性百草枯中毒后应尽早催吐、洗胃和导泻,减少毒物吸收,血液净化和免疫制剂的应用在降低重症患者病死率上未见明显优势.
目的 探討急性百草枯中毒患者的臨床特點,以尋找降低病死率的對策.方法 對我院2008年1月至2012年1月收治的14例重度急性百草枯中毒患者的臨床錶現和治療方法進行迴顧性分析.結果 14例患者中死亡9例,病死率高達64%,7例死于醫院,中毒至死亡時間為40~175 h,2例放棄治療齣院後死亡,死亡原因均為多髒器功能衰竭.存活患者5例,均及時給予催吐、洗胃和導瀉等治療和支持治療,4例患者錶現為非少尿型急性腎功能衰竭.結論 急性百草枯中毒後應儘早催吐、洗胃和導瀉,減少毒物吸收,血液淨化和免疫製劑的應用在降低重癥患者病死率上未見明顯優勢.
목적 탐토급성백초고중독환자적림상특점,이심조강저병사솔적대책.방법 대아원2008년1월지2012년1월수치적14례중도급성백초고중독환자적림상표현화치료방법진행회고성분석.결과 14례환자중사망9례,병사솔고체64%,7례사우의원,중독지사망시간위40~175 h,2례방기치료출원후사망,사망원인균위다장기공능쇠갈.존활환자5례,균급시급여최토、세위화도사등치료화지지치료,4례환자표현위비소뇨형급성신공능쇠갈.결론 급성백초고중독후응진조최토、세위화도사,감소독물흡수,혈액정화화면역제제적응용재강저중증환자병사솔상미견명현우세.
Objective To analysis clinical characteristics of the patients with acute paraquat poisoning,find strategies to reduce the mortality rate.Method A total of 14 patients subjected to acute paraquat poisoning admitted from January 2008 to January 2012 were retrospectively studied.Results The mortality was 64%(9 cases),and survival time ranged from 40 h to 175 h.7 cases died in hospitals,2 cases die at home,and all of them died from multiorgan failure.5 cases who were given gave emetic,gastric lavage,catharsis and symptomatic treatment survived.4 cases of survivors were complicated with non oliguria acute renal failure.Conclusion The patients with acute paraquat poisoning should be given emetic,gastric lavage and catharsis as soon as possible to reduce absorption of the toxic chemical after poisoning.Blood purification and immunosuppressive therapy had no remarkable superiority in decreasing mortality of critical patients.