贵州医药
貴州醫藥
귀주의약
GUIZHOU MEDICAL JOURNAL
2010年
10期
883-886
,共4页
初诊2型糖尿病%血管并发症%患病率
初診2型糖尿病%血管併髮癥%患病率
초진2형당뇨병%혈관병발증%환병솔
Newly-diagnosed type 2 diabetes mellitus Macrovascular complications Prevalence
目的了解初诊2型糖尿病患者慢性并发症的患病率及其相关危险因素。方法对301例初诊2型糖尿病患者依据判断标准分别计算糖尿病各种慢性并发症的患病率;并对慢性并发症的相关因素进行Logistic回归多因素筛查;所有数据采用SPSS 16.0统计软件进行处理。结果 301例初诊2型糖尿病患者中伴糖尿病慢性并发症者194例,占64.5%,其中脑血管病（CVD）、冠心病（CHD）、下肢动脉病变（LEAD）、糖尿病视网膜病变（DR）、糖尿病肾病（DN）及糖尿病神经病变（DNP）的患病率分别为3.7%、9.4%、2.3%、10.6%、18.6%和46.2%;Logistic回归筛查糖尿病并发症的相关危险因素：年龄与大血管并发症呈正相关（OR=1.045,P=0.015）;高密度脂蛋白胆固醇（HDL-C）与大血管并发症呈负相关（OR=0.115,P=0.015）;年龄、病程、收缩压（SDP）及糖化血红蛋白与糖尿病微血管并发症呈正相关（OR值分别为1.048、1.062、1.026及1.161,P值分别为0.000、0.047、0.027及0.021）。结论本研究显示住院初诊2型糖尿病患者的各种慢性并发症患病率已高达3.7%~46.2%,因此,对2型糖尿病患者进行早期积极干预势在必行。
目的瞭解初診2型糖尿病患者慢性併髮癥的患病率及其相關危險因素。方法對301例初診2型糖尿病患者依據判斷標準分彆計算糖尿病各種慢性併髮癥的患病率;併對慢性併髮癥的相關因素進行Logistic迴歸多因素篩查;所有數據採用SPSS 16.0統計軟件進行處理。結果 301例初診2型糖尿病患者中伴糖尿病慢性併髮癥者194例,佔64.5%,其中腦血管病（CVD）、冠心病（CHD）、下肢動脈病變（LEAD）、糖尿病視網膜病變（DR）、糖尿病腎病（DN）及糖尿病神經病變（DNP）的患病率分彆為3.7%、9.4%、2.3%、10.6%、18.6%和46.2%;Logistic迴歸篩查糖尿病併髮癥的相關危險因素：年齡與大血管併髮癥呈正相關（OR=1.045,P=0.015）;高密度脂蛋白膽固醇（HDL-C）與大血管併髮癥呈負相關（OR=0.115,P=0.015）;年齡、病程、收縮壓（SDP）及糖化血紅蛋白與糖尿病微血管併髮癥呈正相關（OR值分彆為1.048、1.062、1.026及1.161,P值分彆為0.000、0.047、0.027及0.021）。結論本研究顯示住院初診2型糖尿病患者的各種慢性併髮癥患病率已高達3.7%~46.2%,因此,對2型糖尿病患者進行早期積極榦預勢在必行。
목적료해초진2형당뇨병환자만성병발증적환병솔급기상관위험인소。방법대301례초진2형당뇨병환자의거판단표준분별계산당뇨병각충만성병발증적환병솔;병대만성병발증적상관인소진행Logistic회귀다인소사사;소유수거채용SPSS 16.0통계연건진행처리。결과 301례초진2형당뇨병환자중반당뇨병만성병발증자194례,점64.5%,기중뇌혈관병（CVD）、관심병（CHD）、하지동맥병변（LEAD）、당뇨병시망막병변（DR）、당뇨병신병（DN）급당뇨병신경병변（DNP）적환병솔분별위3.7%、9.4%、2.3%、10.6%、18.6%화46.2%;Logistic회귀사사당뇨병병발증적상관위험인소：년령여대혈관병발증정정상관（OR=1.045,P=0.015）;고밀도지단백담고순（HDL-C）여대혈관병발증정부상관（OR=0.115,P=0.015）;년령、병정、수축압（SDP）급당화혈홍단백여당뇨병미혈관병발증정정상관（OR치분별위1.048、1.062、1.026급1.161,P치분별위0.000、0.047、0.027급0.021）。결론본연구현시주원초진2형당뇨병환자적각충만성병발증환병솔이고체3.7%~46.2%,인차,대2형당뇨병환자진행조기적겁간예세재필행。
Objective To investigate the prevalence of macrovascular complications and find their risk factors in newly-diagnosed patients with type 2 diabetes mellitus. Methods Data of 301 cases of newly-diagnosed type 2 diabetes were retrospectively studied. Their macrovascular complications were classified according to WHO protocol and criteria. The prevalence of the cerebrovascular disease （CVD）, the cardiovascular disease （CHD）, lower-extremity arterial disease （LEAD） and their risk factors were analyzed. All patients were divided into two groups which were non-complications and complications. The clinical data of two groups of patients were compared. Multivariate logistic regresson model was used to identify independent risk factors for related chronic complications. All data was stored and processed by using SPSS software version 16.0. There were statistically significance （P〈 0. 05）. Results Total of 301 patients, there were diabetic macrovascular complications （15.0%） in 45 cases. The prevalence of CVD, CHD and LEAD were 3.7G, 9.4%and 2.30//00 respectively. In the diabetic patients, there was positive correlation between age and diabetic macrovasuclar complications （OR values 1. 045, P values 0. 015）, there was negative correlation between the high-density lipoprotein cholesterol（HDL-C） and macrovasuclar complications（OR values 0. 115, P values 0. 015）. Conclusion The results were shown that there are higher macrovascular complicatins In newly-diagnosed type 2 diabetes patients. The results reminded us that it is urgent to intervent type 2 diabetes mellitus as early as possible.
