CAJ | 학술논문

目的探讨急性肾功能衰竭的临床病因、分型及治疗效果。方法回顾性分析本院所有透析治疗的88例急性肾功能衰竭(ARF)病人的临床病历资料、肾衰原因、肾衰类型及治疗效果。结果 ARF有肾前性因素者达78.14%，单纯肾实质性病变占20.45%，肾后性原因仅占1.14%；药物引物的ARF占20.45%，以氨基糖甙类抗菌素多见(13/18)；病人死亡率为30.97%，完全治愈率仅为37.5%。结论注意血容量不足的症状与体征，及时扩容，保证肾供血充足可减少ARF的发生及药物性肾毒性的出现；需透析治疗的ARF病人治疗效果欠佳。
목적 탐토급성신공능쇠갈적림상병인、분형급치료효과。방법 회고성분석본원소유투석치료적88례급성신공능쇠갈(ARF)병인적림상병력자료、신쇠원인、신쇠류형급치료효과。결과 ARF유신전성인소자체78.14%，단순신실질성병변점20.45%，신후성원인부점1.14%；약물인물적ARF점20.45%，이안기당대류항균소다견(13/18)；병인사망솔위30.97%，완전치유솔부위37.5%。결론 주의혈용량불족적증상여체정，급시확용，보증신공혈충족가감소ARF적발생급약물성신독성적출현；수투석치료적ARF병인치료효과흠가。
Objective To research the pathogenesis,clinical types andtherapeutic effects of acute renal failure.Method All eighty-eight patients with acute renal failure(ARF) treated by hemodialysis were analyzed retrospectively in our hospital for last more than 4 years,and the etiology,clinical types of ARF and the clinical outcome of treatment were summarized.Results ARF patients with pre-renal reasons were 78.41%,single renal cortex and/or medullary disease leading to ARF were 20.45%,post-renal reason was only 1.14%;ARF induced by drugs were 20.45%,the main drugs were aminoglycosides(13/18);mortality rate was 30.97%,but the complete recovery rate was only 37.5%.Conclusion Clinical doctors must be careful observe the patients complications decrasing signs of the blood volume and supplementing blood volume in timely to avoid renal ischemia,these treatment may prevent ARF and kidney lesion induced by drugs,but the prognosis of patients with hemodialysis in ARF is not good.