中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2012年
8期
986-988
,共3页
李海燕%袁志刚%杨鹏霞%王兰
李海燕%袁誌剛%楊鵬霞%王蘭
리해연%원지강%양붕하%왕란
儿童%眼部肿瘤%病理分析
兒童%眼部腫瘤%病理分析
인동%안부종류%병리분석
Children%Ocular tumor%Pathological analysis
目的 分析儿童眼部肿瘤的构成、分布情况及发病特点.方法 对病理科2000年至2010年10年间收集的410例儿童眼部肿瘤的发病年龄、发病部位和病理类型进行回顾性分析.结果 全部肿瘤的平均发病年龄为(7.08±2.6)岁,眼内肿瘤发病的年龄年龄最小,只有(2.44±1.5)岁,与其他部位肿瘤相比差异有统计学意义(F =15.658,P=0.001).从发病部位来看眼结膜肿物最多152例(37.1%),其次为眼眶肿物84例(20.5%).良性肿瘤362例(88.3%),恶性肿瘤48例(11.7%).其中良性肿瘤中以皮样囊肿最多见72例(19.9%),其次为皮样瘤63例(17.4%)、皮样脂肪瘤57例(15.7%)、乳头瘤33例(9.1%)等多见.恶性肿瘤中以视网膜母细胞瘤最多见43例(89.6%)其次为横纹肌肉瘤2例(4.2%).结论 儿童眼部肿瘤大多与先天和胚胎异常有关,其中结膜肿瘤最多见.良性肿瘤中皮样囊肿最多见,其次为乳头状瘤、炎性增生和各种上皮性囊肿.恶性肿瘤中视网膜母细胞瘤发病率最高,而且恶性肿瘤的发病年龄早于良性肿瘤.
目的 分析兒童眼部腫瘤的構成、分佈情況及髮病特點.方法 對病理科2000年至2010年10年間收集的410例兒童眼部腫瘤的髮病年齡、髮病部位和病理類型進行迴顧性分析.結果 全部腫瘤的平均髮病年齡為(7.08±2.6)歲,眼內腫瘤髮病的年齡年齡最小,隻有(2.44±1.5)歲,與其他部位腫瘤相比差異有統計學意義(F =15.658,P=0.001).從髮病部位來看眼結膜腫物最多152例(37.1%),其次為眼眶腫物84例(20.5%).良性腫瘤362例(88.3%),噁性腫瘤48例(11.7%).其中良性腫瘤中以皮樣囊腫最多見72例(19.9%),其次為皮樣瘤63例(17.4%)、皮樣脂肪瘤57例(15.7%)、乳頭瘤33例(9.1%)等多見.噁性腫瘤中以視網膜母細胞瘤最多見43例(89.6%)其次為橫紋肌肉瘤2例(4.2%).結論 兒童眼部腫瘤大多與先天和胚胎異常有關,其中結膜腫瘤最多見.良性腫瘤中皮樣囊腫最多見,其次為乳頭狀瘤、炎性增生和各種上皮性囊腫.噁性腫瘤中視網膜母細胞瘤髮病率最高,而且噁性腫瘤的髮病年齡早于良性腫瘤.
목적 분석인동안부종류적구성、분포정황급발병특점.방법 대병이과2000년지2010년10년간수집적410례인동안부종류적발병년령、발병부위화병리류형진행회고성분석.결과 전부종류적평균발병년령위(7.08±2.6)세,안내종류발병적년령년령최소,지유(2.44±1.5)세,여기타부위종류상비차이유통계학의의(F =15.658,P=0.001).종발병부위래간안결막종물최다152례(37.1%),기차위안광종물84례(20.5%).량성종류362례(88.3%),악성종류48례(11.7%).기중량성종류중이피양낭종최다견72례(19.9%),기차위피양류63례(17.4%)、피양지방류57례(15.7%)、유두류33례(9.1%)등다견.악성종류중이시망막모세포류최다견43례(89.6%)기차위횡문기육류2례(4.2%).결론 인동안부종류대다여선천화배태이상유관,기중결막종류최다견.량성종류중피양낭종최다견,기차위유두상류、염성증생화각충상피성낭종.악성종류중시망막모세포류발병솔최고,이차악성종류적발병년령조우량성종류.
Objective To explore the classification,distribution and pathogenetic characteristics of ocular tumor in children. Methods Retrospective analysis was taken in age,tumor location and pathological types of 410 children with ocular tumor recruited from Shanxi eye hospital in the year 2000-2010 periods. Results The mean age was 7.08±2.6 years old in all cases.There was significant difference in age of onset among intraocular tumor children comparing to other place tumor by holding on 2.44±1.5 years old (F =15.658,P =0.001).In terms of tumor location,the first two common lesion location were conjunctiva and orbit with 152 (37.1%) and 84 (20.5%) respectively.Among all cases there were 362 (88.3%) benign tumors and 48 (11.7%) malignant ones.The most popular benign tumor was dermoid cyst contributing to 72 (19.9%) followed by dermoid tumor 63 (17.4%),dermatolipoma,57 (15.7%) and papilloma 33 (9.1%),etc.The retinoblastoma held the largest percentage of malignant tumors in children ocular with 43 (89.6%) and followed by rhabdomyosarcoma with 2 (4.2%),etc. Conclusions Ocular tumors in children mainly are congenital and embryonic tumors.The most common ocular tumor in 410 children patients is the conjunctival tumor.Dermoid cysts present the highest prevalence in benign ocular tumor followed by papilloma,inflammatory hyperplasia and epithelium cysts.Among the malignant tumors,retinoblastoma shows the highest prevalence and the age of onset in malignant tumors much younger than benign ocular tumor.