药品评价
藥品評價
약품평개
DRUG REEVALUATION
2013年
12期
18-21
,共4页
便秘%普芦卡必利%5-HT4受体激动剂%心脏安全性
便祕%普蘆卡必利%5-HT4受體激動劑%心髒安全性
편비%보호잡필리%5-HT4수체격동제%심장안전성
Constipation%5-HT4 Receptor Agonist%Prucalopride%Cardiac Safety
普芦卡必利(Prucalopride)对成年女性慢性便秘有确切的疗效和良好的安全性，包括具有心血管基础疾病的老年患者均具有良好的耐受性和安全性。本文从药品性状、药理作用、药代动力学、临床评价、安全性、适应症等方面进行综述，旨在为其临床合理应用提供参考依据。
普蘆卡必利(Prucalopride)對成年女性慢性便祕有確切的療效和良好的安全性，包括具有心血管基礎疾病的老年患者均具有良好的耐受性和安全性。本文從藥品性狀、藥理作用、藥代動力學、臨床評價、安全性、適應癥等方麵進行綜述，旨在為其臨床閤理應用提供參攷依據。
보호잡필리(Prucalopride)대성년녀성만성편비유학절적료효화량호적안전성，포괄구유심혈관기출질병적노년환자균구유량호적내수성화안전성。본문종약품성상、약리작용、약대동역학、림상평개、안전성、괄응증등방면진행종술，지재위기림상합리응용제공삼고의거。
Prucalopride has been confirmed with exact effect and favorable safety for adult women with chronic constipation, and has favorable tolerance and safety for old patients with cardiovascular disease. This article reviews the characteristic, pharmacological action, pharmacokinetics, drug interaction, clinical evaluation, and safety of prucalopride in order to provide scientific foundation for rational therapy.
