中国现代应用药学
中國現代應用藥學
중국현대응용약학
CONTENTS IN BRIEF
2001年
2期
133-134
,共2页
高效液相色谱法%甲磺酸酚妥拉明
高效液相色譜法%甲磺痠酚妥拉明
고효액상색보법%갑광산분타랍명
目的:建立了反向高效液相色谱法测定甲磺酸酚妥拉明的含量的 方法。方 法:采用Symmetry C18硅烷键和硅胶柱,甲醇-水- 冰醋酸-三乙胺(10:10:1:0.1)作为流动相,检测波长为278nm, 峰面积外标法测定。结果 :平均回收率为100.2%(n=11),日内、日间差分别为0.7%和0.8%,在10~250μg范围内线 性关系良好(r=0.9999)。结论:该法简便、准确,结果满意。
目的:建立瞭反嚮高效液相色譜法測定甲磺痠酚妥拉明的含量的 方法。方 法:採用Symmetry C18硅烷鍵和硅膠柱,甲醇-水- 冰醋痠-三乙胺(10:10:1:0.1)作為流動相,檢測波長為278nm, 峰麵積外標法測定。結果 :平均迴收率為100.2%(n=11),日內、日間差分彆為0.7%和0.8%,在10~250μg範圍內線 性關繫良好(r=0.9999)。結論:該法簡便、準確,結果滿意。
목적:건립료반향고효액상색보법측정갑광산분타랍명적함량적 방법。방 법:채용Symmetry C18규완건화규효주,갑순-수- 빙작산-삼을알(10:10:1:0.1)작위류동상,검측파장위278nm, 봉면적외표법측정。결과 :평균회수솔위100.2%(n=11),일내、일간차분별위0.7%화0.8%,재10~250μg범위내선 성관계량호(r=0.9999)。결론:해법간편、준학,결과만의。
OBJECTIVE:The RP-HPLC method was establish ed to assay phentolamine mesylate tablets.METHOD:The RP-HPLC me thod was developed with the following conditions:column,C18(150ⅹ3.9mm,10μm);t he mobile phase:methanol-water-acetic acid-triethylamine(10:10:1:0.1);the wavele ngth of the detector:278nm.RESULTS:The mean recovery of phento lamine was 100.2%.The within dey and day-to-day of variations were 0.7% and 0.8% ,yespectivly The assay linearity was determined over the range of 10-250μg(u=0. 9999).CONCLUSION:The method was simple and accurate with satisf actory results