CAJ | 학술논문

目的分析CYFRA21－1、NSE和CEA在不同组织类型的肺癌中表达的差异。方法采用放免分析对13例正常人和37例肺癌患者进行血清CYFRA21-1、NSE和CEA的检测，统计分析各项指标在正常人、鳞癌、腺癌和小细胞肺癌患者之间的差别。结果 CYFRA21-1在鳞癌、腺癌患者中表达水平较高，与小细胞肺癌及正常人有显著性差异；NSE在小细胞肺癌患者中表达水平较高，与鳞癌、腺癌及正常人有显著性差异；CEA在腺癌患者中表达水平较高，与鳞癌、小细胞肺癌及正常人有显著性差异。结论 CYFRA21-1、NSE和CEA在肺癌中的表达与肺癌的组织类型密切相关。
목적분석CYFRA21－1、NSE화CEA재불동조직류형적폐암중표체적차이。방법채용방면분석대13례정상인화37례폐암환자진행혈청CYFRA21-1、NSE화CEA적검측，통계분석각항지표재정상인、린암、선암화소세포폐암환자지간적차별。결과 CYFRA21-1재린암、선암환자중표체수평교고，여소세포폐암급정상인유현저성차이；NSE재소세포폐암환자중표체수평교고，여린암、선암급정상인유현저성차이；CEA재선암환자중표체수평교고，여린암、소세포폐암급정상인유현저성차이。결론 CYFRA21-1、NSE화CEA재폐암중적표체여폐암적조직류형밀절상관。
Objective　To analyze the different expression of CYFRA21-1，NSE and CEA in varied histologic types of lung carcinoma.Methods　Immunoradiometric assay and statistical analysis was used to study the levels of CYFRA21-1，NSE and CEA in the serum of 13 cases of normal persons, 37 cases of lung cancer patients.Results　The CYFRA21-1 in squamous cell carcinoma or adenocarcionoma was higher than small cell lung cancer or normal persons and the difference was statistically significant. The NSE in small cell lung cancer was significantly higher than squamous cell carcinoma, adenocarcinoma or normal persons. The CEA in adenocarcinoma was significantly higher than squamous cell carcinoma, small cell lung cancer or normal persons.Conclusion　The close relation between the quantity of CYFRA21-1,NSE and CEA in lung cancer and varied histologic types of lung carcinoma was seen.