CAJ | 학술논문

为了了解淫羊藿治疗阳痿的作用机制，采用 Geiess 试剂检测淫羊藿醇提物及灌服淫羊藿醇提物小鼠血清对内皮细胞释放 NO 的影响。结果显示：淫羊藿醇提物直接加入内皮细胞培养液中不影响 NO 产生，120 min，180 min 采集的含淫羊藿醇提物血清能促进 NO 的产生，效应高峰在 120 min。结果提示：促进内皮细胞释放 NO 可能是淫羊藿治疗阳痿的作用机制之一。
위료료해음양곽치료양위적작용궤제，채용 Geiess 시제검측음양곽순제 물급관복음양 곽순제물소서혈청대내피세포석방 NO 적영향。결과현시：음양곽순제물직접가입내피세포 배양액중불영향 NO 산생，120 min，180 min 채집적함음양곽순제물혈청능촉진 NO 적산 생，효응고봉재 120 min。결과제시：촉진내피세포석방 NO 가능시음양곽치료양위적작용 궤제지일。
To investigate the mechanism of Herba Epimedii alcoho l extract for imp otence, Giess reagent was used to observe the effect of the alcohol extract of H erba Epimedii in mice and its effect on release of NO fro m human umbilical vein endothelial cells in vitro was also studied. The results showed that alcoh ol extract of Herba Epimdii had no effect on the release of NO. But the serum co llected from the mice after the medication of alcohol extract of Herba Epimedii for 120min and 180min promoted the production of NO, and the reaction reached th e peak at 120 min. It is indicated that the promotion of NO release from endothe lial cells may be one of the mechanisms of Herba Epimedii for impotence.