CAJ | 학술논문

目的对40例原发性鼻腔非霍奇金淋巴瘤(PNNHL)进行回顾性分析，以探讨其最佳治疗选择及其预后有关的因素。方法将40例患者分为单纯放疗，单纯化疗及综合治疗三组，对其1、3、5年生存率作相关比较。生存率用寿命表法统计，并作多因素卡方检验。结果通过5年生存率(SR5)比较结果表明，单纯放疗及综合治疗优于单纯化疗，临床Ⅰ、Ⅱ期的疗效优于Ⅲ、Ⅳ期。结论放射治疗是PNNHL治疗的最佳选择。临床分期早且无消瘦、发热、盗汗症状及采用放疗为主治疗是预后好的主要因素。
목적대40례원발성비강비곽기금림파류(PNNHL)진행회고성분석，이탐토기최가치료선택급기예후유관적인소。방법장40례환자분위단순방료，단순화료급종합치료삼조，대기1、3、5년생존솔작상관비교。생존솔용수명표법통계，병작다인소잡방검험。결과통과5년생존솔(SR5)비교결과표명，단순방료급종합치료우우단순화료，림상Ⅰ、Ⅱ기적료효우우Ⅲ、Ⅳ기。결론방사치료시PNNHL치료적최가선택。림상분기조차무소수、발열、도한증상급채용방료위주치료시예후호적주요인소。
Objective A retrospective analysis of forty cases with primarynasal non-Hodgkin lymphoma(PNNHL) was performed to investigate its optimal choice of treatment and prognosis-related factors.MethodsForty cases were divided into three groups--(1)Treated with radiotherapy alone;(2)treated with chemotherapy alone;and (3)treated by combined therapy. The clinical effects of three groups were compared each other using 1,3 and 5 year-survival rates. The survival rat e was statistically calculated by lifetable and multiple factor log-rank test . Results Having compared with the five-year survival rates(SR5),the therap eutic efficacy in first and third groups was better than that in second group; whereas that of patients in stage Ⅰ and Ⅱ was better than those in stage Ⅲ and Ⅳ. Conclusions The optimum choice of treatment for PNNHL is radiotherapy. The main favorite factors of prognosis could be the earlier clinical stage; without symptoms of emaciation, fever and night sweating; as well as adopting radiotherapy as the major measure of treatment.