CAJ | 학술논문

目的探讨肿瘤标志物联合检测对恶性肿瘤的诊断意义.方法选取病理诊断为恶性肿瘤的病例,采用电化学发光法检测其血清样本中肿瘤标志物含量.结果 127例恶性肿瘤样本中,所检指标均正常者26例,占总样本数的20.5%;只有1项检测指标异常者47例,占总样本数的37.0%;2项及2项以上检测指标异常者55例,占总样本数的42.5%.结论肿瘤标志物不能作为恶性肿瘤诊断的首选指标,只能作为辅助性诊断依据;所检肿瘤标志物无严格的组织器官特异性,但在某些器官有相对高的检出率;肿瘤标志物联合检测可大大提高肿瘤的检出率,从而降低单一肿瘤标志物检测的漏诊风险.
목적 탐토종류표지물연합검측대악성종류적진단의의.방법 선취병리진단위악성종류적병례,채용전화학발광법검측기혈청양본중종류표지물함량.결과 127례악성종류양본중,소검지표균정상자26례,점총양본수적20.5%;지유1항검측지표이상자47례,점총양본수적37.0%;2항급2항이상검측지표이상자55례,점총양본수적42.5%.결론 종류표지물불능작위악성종류진단적수선지표,지능작위보조성진단의거;소검종류표지물무엄격적조직기관특이성,단재모사기관유상대고적검출솔;종류표지물연합검측가대대제고종류적검출솔,종이강저단일종류표지물검측적루진풍험.
Objective To research the signifcance of combined-examination of tumour markers for malignant tumour diagnosis.Methods Choosing malignant tumour cases diagnosed by our pathology laboratory, and then examining the contents of tumour markers in the serum from chosen cases by means of electrochemiluminescence.Results There are 26 cases of patients, whose results are totally normal,holding 20.5% in 127 cases.47 cases have only one abnormal result of tumour marker,holding 37.0% in 127 cases.55 cases with two or more abnormal result of tumour markers,holding 42.5% in the total samples.Conclusion :Tumour marker cannot be the first choice for tumour diagnosis,but it can be used as auxilary diagnostic evidence.All measured tumour markers have no strict specificity for tissues or organs,but have higher positive rate in some organs. Combined measurement of tumour markers can increase the positive rate of tumour detection,therefore,reduce the risk of missed diagnosis caused by examining one tumour marker only.