中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2010年
35期
1-3
,共3页
吴建国%薛绪潮%毕建威%方国恩
吳建國%薛緒潮%畢建威%方國恩
오건국%설서조%필건위%방국은
C反应蛋白质%降钙素%多器官功能衰竭%多发伤
C反應蛋白質%降鈣素%多器官功能衰竭%多髮傷
C반응단백질%강개소%다기관공능쇠갈%다발상
C-reactive protein%Calcitonin%Multiple organ failure%Multiple trauma
目的 探讨多发伤患者外周血C反应蛋白(CRP)和降钙素原(PCT)与多器官功能障碍综合征(MODS)的相关性.方法 将136例多发伤患者按治疗过程中有无MODS发生分为MODS组(49例)和非MODS组(87例),另选50例健康志愿者作为对照组,检测三组患者外周血不同时间点CRP和PCT含量.结果 MODS组的外周血CRP含量的最高值出现在伤后48 h[(38.7±2.7)mg/L],且在伤后各时间点与非MODS组及对照组比较差异有统计学意义(P＜0.05).MODS组外周血PCT含量的最高值出现在伤后24h[(20.3±1.7)μg/L],且在伤后各时间点与非MODS组及对照组比较差异有统计学意义(P＜0.05).结论 创伤后急性期CRP和PCT含量与MODS的发生均具有相关性.联合测定对MODS预测更为可靠,具有较高的临床价值.
目的 探討多髮傷患者外週血C反應蛋白(CRP)和降鈣素原(PCT)與多器官功能障礙綜閤徵(MODS)的相關性.方法 將136例多髮傷患者按治療過程中有無MODS髮生分為MODS組(49例)和非MODS組(87例),另選50例健康誌願者作為對照組,檢測三組患者外週血不同時間點CRP和PCT含量.結果 MODS組的外週血CRP含量的最高值齣現在傷後48 h[(38.7±2.7)mg/L],且在傷後各時間點與非MODS組及對照組比較差異有統計學意義(P＜0.05).MODS組外週血PCT含量的最高值齣現在傷後24h[(20.3±1.7)μg/L],且在傷後各時間點與非MODS組及對照組比較差異有統計學意義(P＜0.05).結論 創傷後急性期CRP和PCT含量與MODS的髮生均具有相關性.聯閤測定對MODS預測更為可靠,具有較高的臨床價值.
목적 탐토다발상환자외주혈C반응단백(CRP)화강개소원(PCT)여다기관공능장애종합정(MODS)적상관성.방법 장136례다발상환자안치료과정중유무MODS발생분위MODS조(49례)화비MODS조(87례),령선50례건강지원자작위대조조,검측삼조환자외주혈불동시간점CRP화PCT함량.결과 MODS조적외주혈CRP함량적최고치출현재상후48 h[(38.7±2.7)mg/L],차재상후각시간점여비MODS조급대조조비교차이유통계학의의(P＜0.05).MODS조외주혈PCT함량적최고치출현재상후24h[(20.3±1.7)μg/L],차재상후각시간점여비MODS조급대조조비교차이유통계학의의(P＜0.05).결론 창상후급성기CRP화PCT함량여MODS적발생균구유상관성.연합측정대MODS예측경위가고,구유교고적림상개치.
Objective To investigate the relation of the peripheral blood C-reactive protein (CRP)and procalcitonin (PCT) and multiple organ dysfunction syndrome( MODS ) for patients with multiple trauma.Methods A total of 136 patients with multiple trauma were divided into MODS group (49 cases) and non MODS group (87 cases),and 50 healthy volunteers were chosen as control group. Peripheral blood CRP and PCT concentration were detected at different times. Results The highest concentration of peripheral blood CRP in MODS group was appeared on 48 h [(38.7 ± 2.7) mg/L], CRP concentrations in MODS group were significantly different with non MODS group and control group (P ＜0.05). The highest concentration of peripheral blood PCT in MODS group was appeared on 24 h [(20.3 ± 1.7)μ g/L], PCT concentrations in MODS group were significantly different with non MODS group and control group (P＜ 0.05). Conclusions CRP and PCT are relevant to the occurrence of MODS in trauma acute stage. The observation of peripheral blood CRP and PCT concentrations can predict the occurrence of MODS.
