中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
11期
1472-1474
,共3页
脑血管意外%复发%随访研究%Cox回归分析
腦血管意外%複髮%隨訪研究%Cox迴歸分析
뇌혈관의외%복발%수방연구%Cox회귀분석
Cerebrovascular accident%Recurrence%follow-up study%Cox regression analysis
目的 探讨脑卒中复发的主要影响因素.方法 2 065例脑卒中新发病例为研究人群,随访患者的复发情况,调查影响复发的各种因素.随访时间为3年.应用Cox比例风险回归模型对影响脑卒中复发的各种因素进行单因素和多因素分析.结果 截至随访终点,受访病例共1 881例,失访病例184例.复发病例327例(17.38%),6个月内复发45例(13.76%),6个月至1年复发68例(20.80%),1～2年复发97例(29.66%),～3年复发117例(35.78%).单因素Cox回归分析:高龄(RR=1.48)、吸烟(RR=1.35)、脂肪摄入(RR=1.83)、高血压史(RR:2.54)、糖尿病史(RR=1.72)、高脂血症(RR=1.83)、脑卒中家族史(RR=2.62)、抑郁(RR=1.84)、生活事件(RR=2.53)、纤维蛋白原(RR=1.75)、颈动脉斑块(RR=2.68)为脑卒中复发的危险因素;女性(RR=0.64)、运动(RR=0.33)、社会支持(RR=0.36)为脑卒中复发的保护因素.多因素Cox回归分析表明:高血压史(RR=1.86)、高脂血症(RR=1.95)、脑卒中家族史(RR=2.62)、生活事件(RR=2.38)、颈动脉斑块(RR=2.77)是引起脑卒中复发的危险因素;运动(RR=0.35)、社会支持(RR=0.32)是脑卒中复发的保护因素.结论 对脑卒中患者的高血压史、高脂血症、脑卒中家族史的预防、多参加体育运动、增强对生活事件的应对能力,有助于脑卒中复发的预防.
目的 探討腦卒中複髮的主要影響因素.方法 2 065例腦卒中新髮病例為研究人群,隨訪患者的複髮情況,調查影響複髮的各種因素.隨訪時間為3年.應用Cox比例風險迴歸模型對影響腦卒中複髮的各種因素進行單因素和多因素分析.結果 截至隨訪終點,受訪病例共1 881例,失訪病例184例.複髮病例327例(17.38%),6箇月內複髮45例(13.76%),6箇月至1年複髮68例(20.80%),1～2年複髮97例(29.66%),～3年複髮117例(35.78%).單因素Cox迴歸分析:高齡(RR=1.48)、吸煙(RR=1.35)、脂肪攝入(RR=1.83)、高血壓史(RR:2.54)、糖尿病史(RR=1.72)、高脂血癥(RR=1.83)、腦卒中傢族史(RR=2.62)、抑鬱(RR=1.84)、生活事件(RR=2.53)、纖維蛋白原(RR=1.75)、頸動脈斑塊(RR=2.68)為腦卒中複髮的危險因素;女性(RR=0.64)、運動(RR=0.33)、社會支持(RR=0.36)為腦卒中複髮的保護因素.多因素Cox迴歸分析錶明:高血壓史(RR=1.86)、高脂血癥(RR=1.95)、腦卒中傢族史(RR=2.62)、生活事件(RR=2.38)、頸動脈斑塊(RR=2.77)是引起腦卒中複髮的危險因素;運動(RR=0.35)、社會支持(RR=0.32)是腦卒中複髮的保護因素.結論 對腦卒中患者的高血壓史、高脂血癥、腦卒中傢族史的預防、多參加體育運動、增彊對生活事件的應對能力,有助于腦卒中複髮的預防.
목적 탐토뇌졸중복발적주요영향인소.방법 2 065례뇌졸중신발병례위연구인군,수방환자적복발정황,조사영향복발적각충인소.수방시간위3년.응용Cox비례풍험회귀모형대영향뇌졸중복발적각충인소진행단인소화다인소분석.결과 절지수방종점,수방병례공1 881례,실방병례184례.복발병례327례(17.38%),6개월내복발45례(13.76%),6개월지1년복발68례(20.80%),1～2년복발97례(29.66%),～3년복발117례(35.78%).단인소Cox회귀분석:고령(RR=1.48)、흡연(RR=1.35)、지방섭입(RR=1.83)、고혈압사(RR:2.54)、당뇨병사(RR=1.72)、고지혈증(RR=1.83)、뇌졸중가족사(RR=2.62)、억욱(RR=1.84)、생활사건(RR=2.53)、섬유단백원(RR=1.75)、경동맥반괴(RR=2.68)위뇌졸중복발적위험인소;녀성(RR=0.64)、운동(RR=0.33)、사회지지(RR=0.36)위뇌졸중복발적보호인소.다인소Cox회귀분석표명:고혈압사(RR=1.86)、고지혈증(RR=1.95)、뇌졸중가족사(RR=2.62)、생활사건(RR=2.38)、경동맥반괴(RR=2.77)시인기뇌졸중복발적위험인소;운동(RR=0.35)、사회지지(RR=0.32)시뇌졸중복발적보호인소.결론 대뇌졸중환자적고혈압사、고지혈증、뇌졸중가족사적예방、다삼가체육운동、증강대생활사건적응대능력,유조우뇌졸중복발적예방.
Objective To explore the main influencing factors of recurrent stroke.Methods 2 065 new stroke patients were selected as study populations.The recurrent stroke status and kinds of influencing factors were followed up.The follow-up study time was 3 years.Single factor and multi-factor analysis methods were carried out for influencing factom of recurrent stroke by Cox proportional hazaIds regression models.Results By the end.1 881 pa%);45 patients were recurrent in 6accepted visit,184 were lost follow-up.327 patients were recurrent(17.38tients months(13.76%);68 patients were recurrent during 6 months to 1 year(20.80%);97 patients were recurrent during 1 year to 2 years(29.66%);117 patients were recurrent after 3 years(35.78%).Single factor Cox regression analysis:The risk factors of recurrent stroke were advanced age(RR=1.48),smoking(RR=1.35),fat intake(RR=1.83),hypertension history(RR=2.54),diabetes history(RR=1.72),high lipemia(RR=1.83),stroke family history(RR=2.62),depression(RR=1.84),life events(RR=2.53),fibrinogen(RR=1.75),carotid plaques(RR=2.68);The protecting favors of recurrent stroke were female(RR=0.64),sports(RR=0.33),social support(RR=0.36).Multi-factor Cox regression analysis:the risk factors of recurrent stroke were hypertension history(RR=1.86),high lipemia(RR=1.95),stroke family history(RR=2.62),life events(RR=2.38),carotid plaques(RR=2.77);The protecting factors of recurrent stroke were sports(RR:0.35),social support(RR=0.32).Conclusion The prevention of hypertension history,high lipemia,the family history of stroke,more supports and the high ability of answering life events could help to prevent the recurrent stroke.
