CAJ | 학술논문

目的为调查中国健康母猪体内猪链球菌的主要致病血清型分布和不同血清型猪链球菌的耐药性差异.方法采集国内10个省市的健康母猪扁桃体并从中分离鉴定出猪链球菌421株,经与标准血清的凝集反应了解其主要致病血清型分布,并用微量肉汤法对不同血清型的猪链球菌进行耐药性检测,经统计分析了解小同血清型猪链球菌的耐药性差异.结果健康母猪体内所分离猪链球菌的优势(致病)血清型依次为9、3和7型,所占比例分别为26.6%、23.5%和15.7%.在能分型的其他血清型中,猪链球菌2型所占的比例为7.4%;耐药性研究结果表明,不同血清型的猪链球菌对抗菌药物的耐药性不同,猪链球菌2型对所测12种药物的敏感性最强.结论健康母猪体内猪链球菌的致病血清型分布结果再次证明猪链球菌是一种条件性致病菌,不同血清型的猪链球菌感染应根据抗生素敏感件测试结果选用不同的药物进行合理防治.
목적 위조사중국건강모저체내저련구균적주요치병혈청형분포화불동혈청형저련구균적내약성차이.방법 채집국내10개성시적건강모저편도체병종중분리감정출저련구균421주,경여표준혈청적응집반응료해기주요치병혈청형분포,병용미량육탕법대불동혈청형적저련구균진행내약성검측,경통계분석료해소동혈청형저련구균적내약성차이.결과 건강모저체내소분리저련구균적우세(치병)혈청형의차위9、3화7형,소점비례분별위26.6%、23.5%화15.7%.재능분형적기타혈청형중,저련구균2형소점적비례위7.4%;내약성연구결과표명,불동혈청형적저련구균대항균약물적내약성불동,저련구균2형대소측12충약물적민감성최강.결론 건강모저체내저련구균적치병혈청형분포결과재차증명저련구균시일충조건성치병균,불동혈청형적저련구균감염응근거항생소민감건측시결과선용불동적약물진행합리방치.
Objective To determine the distributions of major pathogenic capsular types and in vitro antimicrobial susceptibility of different serotypes of Streptococcus suis isolated from clinically healthy sows in China. Methods Tonsil specimens of clinically healthy sows from 10 different provinces in China were collected, a total of 421 S.suis were isolated. Capsular types of S.suis were decided using the sera agglutination reaction. Antimicrobial susceptibility testing was performed using a broth microdilution method and the differences between serotypes were decided statistically. Results The prevalent capsular types of S.suis isolated from clinically healthy sows were 9(26.6% ), 3 (23.5%) and 7(15.7% ) types, respectively. 7.4% of isolates were confirmed to be S.suis type 2. Overall, differences in antimicrobial susceptibility among serotypes of S. suis were found. By comparison, lower resistance was observed for S.suis type 2 from clinically healthy sows. Conclusion The prevalence of pathogenic S.suis serotypes from clinically healthy sows again indicates S.suis is a conditional pathogenic bacterium. Differential prevention and treatment regimes should be considered according to antimicrobial susceptibility of different serotypes of S.suis.