中国地方病学杂志
中國地方病學雜誌
중국지방병학잡지
CHINESE JOURNAL OF ENDEMIOLOGY
2010年
3期
299-302
,共4页
滕瑞涛%王久春%张恩仁%肖长礼%苏秋菊%孙素莲%王健辉%赵伟光%高嵘%刘万洋%蒋恩耀%徐军%赵明亮
滕瑞濤%王久春%張恩仁%肖長禮%囌鞦菊%孫素蓮%王健輝%趙偉光%高嶸%劉萬洋%蔣恩耀%徐軍%趙明亮
등서도%왕구춘%장은인%초장례%소추국%손소련%왕건휘%조위광%고영%류만양%장은요%서군%조명량
碘%缺乏症%儿童%智力
碘%缺乏癥%兒童%智力
전%결핍증%인동%지력
Iodine%Deficiency disease%Children%Intelligence
目的 了解和比较辽宁省碘缺乏病病区不同补碘时期出生儿童智力水平.方法 1900-2007年,在辽宁省的6个碘缺乏病病区县(市、区)各选出1个乡,其中轻中重病区乡各2个.在6个乡的10所学校中,以病区供应碘盐初期(1978-1980年)、非碘盐充销期(1981-1990年)、恢复普及碘盐期(1991-1995年)、全民食盐加碘期(1996-2000年)出生的7～14岁儿童为凋查对象,用中国联合型瑞文测验(CRT-C)和第二版农村儿童智商(intelligence quotient,IQ)常模测试(CRT-RC2)检查儿童IQ.结果 病区儿童IQ在非碘盐充销期(91.9±14.3)明显低于供应碘盐初期(95.8±14.6,q=8.60,P<0.01),恢复普及碘盐期(99.7 ±14.7)明显高于供应碘盐初期、非碘盐充销期(q值分别为9.53、18.13,P均<0.01),全民食盐加碘期(104.3±14.9)明显高于供应碘盐初期、非碘盐充销期、恢复普及碘盐期(q值分别为20.00、28.00、10.46,P均<0.01).儿童智力落后率(IQ≤69)在非碘盐充销期(6.7%,88/1314)高于供应碘盐初期(4.4%,21/471,χ2=3.85,P<0.05),恢复普及碘盐期(3.3%,48/1470)明显低于非碘盐充销期(χ2=15.37,P<0.01),全民食盐加碘期(2.7%,36/1344)低于供应碘盐初期(χ2=4.41,P<0.05)和非碘盐充销期(χ2=26.34,P<0.01).供应碘盐初期各年度出生儿童IQ及智力落后率未有明显变化;非碘盐充销期的10年间,出生儿童IQ呈"∪"形降升,智力落后率则呈"∩"形升降;恢复普及碘盐时期出生儿童IQ逐年提高,智力落后率逐年降低;全民食盐加碘期各年度儿童IQ继续上升,智力落后率降到历史最低程度.结论 碘缺乏病病区非碘盐充销时期出生儿童智力水平明显低于供应碘盐初期儿童,全民食盐加碘期病区出生儿童智力水平较供应碘盐初期和恢复普及碘盐时期出生儿童有明显提高.
目的 瞭解和比較遼寧省碘缺乏病病區不同補碘時期齣生兒童智力水平.方法 1900-2007年,在遼寧省的6箇碘缺乏病病區縣(市、區)各選齣1箇鄉,其中輕中重病區鄉各2箇.在6箇鄉的10所學校中,以病區供應碘鹽初期(1978-1980年)、非碘鹽充銷期(1981-1990年)、恢複普及碘鹽期(1991-1995年)、全民食鹽加碘期(1996-2000年)齣生的7～14歲兒童為凋查對象,用中國聯閤型瑞文測驗(CRT-C)和第二版農村兒童智商(intelligence quotient,IQ)常模測試(CRT-RC2)檢查兒童IQ.結果 病區兒童IQ在非碘鹽充銷期(91.9±14.3)明顯低于供應碘鹽初期(95.8±14.6,q=8.60,P<0.01),恢複普及碘鹽期(99.7 ±14.7)明顯高于供應碘鹽初期、非碘鹽充銷期(q值分彆為9.53、18.13,P均<0.01),全民食鹽加碘期(104.3±14.9)明顯高于供應碘鹽初期、非碘鹽充銷期、恢複普及碘鹽期(q值分彆為20.00、28.00、10.46,P均<0.01).兒童智力落後率(IQ≤69)在非碘鹽充銷期(6.7%,88/1314)高于供應碘鹽初期(4.4%,21/471,χ2=3.85,P<0.05),恢複普及碘鹽期(3.3%,48/1470)明顯低于非碘鹽充銷期(χ2=15.37,P<0.01),全民食鹽加碘期(2.7%,36/1344)低于供應碘鹽初期(χ2=4.41,P<0.05)和非碘鹽充銷期(χ2=26.34,P<0.01).供應碘鹽初期各年度齣生兒童IQ及智力落後率未有明顯變化;非碘鹽充銷期的10年間,齣生兒童IQ呈"∪"形降升,智力落後率則呈"∩"形升降;恢複普及碘鹽時期齣生兒童IQ逐年提高,智力落後率逐年降低;全民食鹽加碘期各年度兒童IQ繼續上升,智力落後率降到歷史最低程度.結論 碘缺乏病病區非碘鹽充銷時期齣生兒童智力水平明顯低于供應碘鹽初期兒童,全民食鹽加碘期病區齣生兒童智力水平較供應碘鹽初期和恢複普及碘鹽時期齣生兒童有明顯提高.
목적 료해화비교요녕성전결핍병병구불동보전시기출생인동지력수평.방법 1900-2007년,재요녕성적6개전결핍병병구현(시、구)각선출1개향,기중경중중병구향각2개.재6개향적10소학교중,이병구공응전염초기(1978-1980년)、비전염충소기(1981-1990년)、회복보급전염기(1991-1995년)、전민식염가전기(1996-2000년)출생적7～14세인동위조사대상,용중국연합형서문측험(CRT-C)화제이판농촌인동지상(intelligence quotient,IQ)상모측시(CRT-RC2)검사인동IQ.결과 병구인동IQ재비전염충소기(91.9±14.3)명현저우공응전염초기(95.8±14.6,q=8.60,P<0.01),회복보급전염기(99.7 ±14.7)명현고우공응전염초기、비전염충소기(q치분별위9.53、18.13,P균<0.01),전민식염가전기(104.3±14.9)명현고우공응전염초기、비전염충소기、회복보급전염기(q치분별위20.00、28.00、10.46,P균<0.01).인동지력락후솔(IQ≤69)재비전염충소기(6.7%,88/1314)고우공응전염초기(4.4%,21/471,χ2=3.85,P<0.05),회복보급전염기(3.3%,48/1470)명현저우비전염충소기(χ2=15.37,P<0.01),전민식염가전기(2.7%,36/1344)저우공응전염초기(χ2=4.41,P<0.05)화비전염충소기(χ2=26.34,P<0.01).공응전염초기각년도출생인동IQ급지력락후솔미유명현변화;비전염충소기적10년간,출생인동IQ정"∪"형강승,지력락후솔칙정"∩"형승강;회복보급전염시기출생인동IQ축년제고,지력락후솔축년강저;전민식염가전기각년도인동IQ계속상승,지력락후솔강도역사최저정도.결론 전결핍병병구비전염충소시기출생인동지력수평명현저우공응전염초기인동,전민식염가전기병구출생인동지력수평교공응전염초기화회복보급전염시기출생인동유명현제고.
objecfive To know and compare the intelligence level of children born in different time periods in regions with iodine deficiency disorders(IDD)in Liaoning province.Methods All 7-14 year-old children from ten schools were chosen as the subjects respectively from six villages in each of the six counties and in regions with iodine deficiency,who were respectively born at the initialization of iodinated salt supplying period(1978-1980);non-iodinated salt supplying period(1981-1990);recovery of supplied iodized salt period(1991-1995);universal iodized salt period(1996-2000),respectively.Intelligence quotient(IQ)was measured by Combined Ravens Test in China(CRT-C)and Combined Ravens Test-the Rural,in China,2nd edition(CRT-RC2).Results IQ of children during the non-iodized salt period(91.9±14.3)was significantly lower than the initial supply of iodized salt period(95.8±14.6,q=8.60,P<0.01),recovery of supplied iodized salt period(99.7±14.7)was significantly higher than the initial supply of iodized salt period, non-iodized salt sales period(q = 9.53, 18.13, all P < 0.01 ),universal salt iodization( 104.3 ± 14.9) was significantly higher than the initial supply of iodized salt period, non-iodized salt sales period, recovery of supplied salt iodization(q = 20.00,28.00,10.46, all P < 0.01). Children's rate of mental retardation (IQ≤69) was higher in non-iodinated salt supplying period (6.7%, 88/1314 ) than the initial supply of iodized salt (4.4%, 21/471, χ2 = 3.85, P < 0.05), recovery of supplied iodized salt period(3.3%,48/1470) was significantly lower than non-iodinzed salt supplying period (χ2 = 15.37, P < 0.01), universal salt iodization period(2.7%, 36/1344) was lower than the initial supply of iodized salt period(χ2 = 4.41, P < 0.05) and non-iodinzed salt supplying period(χ2 = 26.34, P < 0.01 ). The IQ and intelligent retarded rates in children born during the initial years of iodinated salt supplying period were not different. The IQ of the children during ten years of non-iodized salt supplying period fluctuated in a "∪" curve, while the intelligent retardation rates in a "∩" curve.The children born during the period of recovery supplied iodized salt increased their IQ and lowered the retardation rates year after year. The IQ of the children in universal iodized salt period kept on increasing while intelligent retarded rates reduced to the lowest level. Conclusions The intelligence level of children born in regions with IDD during non-iodized salt supplying period is remarkably lower than that of the beginning years of iodinated salt supplying period. The intelligence level of children born after universal iodized salt period is remarkably higher than that of the initial iodinated salt supplying period and recovery of supplied iodized salt period, respectively.
