中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
7期
762-764
,共3页
王梦娟%刘长山%王峥%王雪艳%张奕
王夢娟%劉長山%王崢%王雪豔%張奕
왕몽연%류장산%왕쟁%왕설염%장혁
肺炎%肺炎支原体%阿奇霉素%儿童
肺炎%肺炎支原體%阿奇黴素%兒童
폐염%폐염지원체%아기매소%인동
Pneumonia%Mycoplasma pneumonia%Azithromycin%Children
目的 观察希舒美针剂治疗肺炎支原体肺炎的临床疗效.方法 将44例肺炎支原体肺炎住院患儿分为2组,分别用希舒美针剂(阿奇霉素,辉瑞制药)和国产阿奇霉素治疗,观察比较2组的临床症状、体征的改善情况.结果 希舒美组25例,1周后治愈17例,显效2例,好转6例,有效率(有效为治愈+显效)76.00%(19/25).对照组19例,治愈5例,显效9例,好转4例,无变化1例,有效率73.68%(14/19).2组对肺炎支原体肺炎治疗均有效,2组有效率比较差异无统计学意义(x2=0.03,P>0.05).但比较2组1周治愈率(x2=7.50,P<0.05)、退热时间(t=34.05.P<0.05)和啰音消失时间(t=2.39,P<0.05),希舒美组均优于对照组,差异均有统计学意义(P均<0.05).结论 希舒美针剂治疗肺炎支原体肺炎疗效好,在改善临床症状上具有一定优越性.
目的 觀察希舒美針劑治療肺炎支原體肺炎的臨床療效.方法 將44例肺炎支原體肺炎住院患兒分為2組,分彆用希舒美針劑(阿奇黴素,輝瑞製藥)和國產阿奇黴素治療,觀察比較2組的臨床癥狀、體徵的改善情況.結果 希舒美組25例,1週後治愈17例,顯效2例,好轉6例,有效率(有效為治愈+顯效)76.00%(19/25).對照組19例,治愈5例,顯效9例,好轉4例,無變化1例,有效率73.68%(14/19).2組對肺炎支原體肺炎治療均有效,2組有效率比較差異無統計學意義(x2=0.03,P>0.05).但比較2組1週治愈率(x2=7.50,P<0.05)、退熱時間(t=34.05.P<0.05)和啰音消失時間(t=2.39,P<0.05),希舒美組均優于對照組,差異均有統計學意義(P均<0.05).結論 希舒美針劑治療肺炎支原體肺炎療效好,在改善臨床癥狀上具有一定優越性.
목적 관찰희서미침제치료폐염지원체폐염적림상료효.방법 장44례폐염지원체폐염주원환인분위2조,분별용희서미침제(아기매소,휘서제약)화국산아기매소치료,관찰비교2조적림상증상、체정적개선정황.결과 희서미조25례,1주후치유17례,현효2례,호전6례,유효솔(유효위치유+현효)76.00%(19/25).대조조19례,치유5례,현효9례,호전4례,무변화1례,유효솔73.68%(14/19).2조대폐염지원체폐염치료균유효,2조유효솔비교차이무통계학의의(x2=0.03,P>0.05).단비교2조1주치유솔(x2=7.50,P<0.05)、퇴열시간(t=34.05.P<0.05)화라음소실시간(t=2.39,P<0.05),희서미조균우우대조조,차이균유통계학의의(P균<0.05).결론 희서미침제치료폐염지원체폐염료효호,재개선림상증상상구유일정우월성.
Objective To observe the effect Azithromycin injection in the treatment of mycoplasma pneumoniae pneumonia ( MPP) in children. Methods Forty-four children of mycoplasma pneumoniae pneumonia were randomly divided into two groups, the Azithromycin group ( treat by Azithromycin, made by Pfizer) and the control group (treat by domestic Azithromycin) respectively. Improvement in symptoms and signs between the two groups were observed and compared. Results There were 25 cases in the Azithromycin group, of which,after a week, 17 cases cured,2 cases got better significantly and 6 cases got better. The effective ratio was 76. 00% ( 19/25 ). There were 19 cases in the control group, of which 5 cases cured, 9 cases got better significantly ,4 cases got better and 1 case no change. The effective ratio was 73. 68% (14/19). There was no statistical significance in the effective ratio between the two groups ( x2 = 0. 03, P > 0. 05). However, the Azithromycin group was superior to the control group both in the one week cure rate (t = 7.50,P< 0.05) and on defervescence time (t = 34. 05, P < 0. 05 ) and rales disappearance (t = 2. 39, P < 0. 05 ). Conclusion Azithromycin injection is more effective than domestic Azithromycin in the treatment of mycoplasma pneumoniae pneumonia,especially in the aspect of improving symptoms.
