中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2012年
8期
697-702
,共6页
糖尿病,2型%移民%患病率%危险因素%非移民
糖尿病,2型%移民%患病率%危險因素%非移民
당뇨병,2형%이민%환병솔%위험인소%비이민
Diabetes mellitus,type 2%Emigrants and immigrants%Prevalence%Risk factor%Nonmigrants
目的 调查湖北宜昌市夷陵区三峡坝区35岁以上就地后靠移民与非移民的2型糖尿病患病情况,分析其影响因素.方法 采用多阶段整群随机抽样的方式,于2007年9-12月在湖北省宜昌市夷陵区调查了35岁以上农村居民9865名,其中移民1949名,非移民7916名.问卷调查收集了调查对象的人口学特征、移民信息、生活方式,以及糖尿病、高血压等慢性病信息.采集空腹8h静脉血,检测FBG、TG、TC、HDL-C、LDL-C.对空腹血糖≥6.1 mmol/L的调查对象进行葡萄糖负荷后2h血糖检测.同时测量身高、体重、腰围、臀围1和血压.用2000年全国人口普查数据对2型糖尿病患病率进行标准化.采用多因素logistic回归方法分析2型精尿病的相关因素.结果 非移民2型糖尿病患病率为3.93% (310/7885),男性为3.90% (129/3304),女性为3.95%( 181/4581);移民的糖尿病患病率为6.55%(127/1939),男性为6.85%( 52/759),女性为6.36%(75/1180),移民的糖尿病患病率高于非移民(总体比较:x2=25.10,男性比较:x2=12.59,女性比较:x2=12.78,P值均<0.01).移民和非移民的糖尿病标化患病率分别为6.63%和4.01%;非移民男性2型糖尿病标化患病率为3.87%,女性为4.15%;移民男性2型糖尿病标化患病率为6.92%,移民女性为6.33%.多因素logistic回归分析结果显示,年龄增长(相比35~ 44岁,45~54岁:OR=1.45,95% CI:1.07~1.95;55 ~64岁:0R=2.08,95%C1:1.53 ~2.84;≥65岁:OR=1.85,95% CI:1.25~2.75)、糖尿病遗传史(OR =2.83,95% CI:1.70 ~4.72)、超重肥胖(超重:OR=1.36,95%CI:1.05 ~ 1.78;肥胖:OR=2.11;95% CI:1.47~3.01)、中心性肥胖(OR=1.84;95% CI:1.39~2.44);TG异常(OR=1.54,95%CI:1.21~1.97);TC异常(OR=1.40;95% CI:1.11~1.77);LDL-C异常(OR=1.82,95% CI:1.19~2.79)是2型糖尿病危险因素.经常、规律体力活动(OR =0.57,95% CI:0.45 ~0.72)是2型糖尿病的保护因素.结论 移民2型糖尿病患病率高于非移民;年龄、体力活动、糖尿病遗传史、超重肥胖、中心性肥胖、TG、TC、LDL-C是2型糖尿病的影响因素.
目的 調查湖北宜昌市夷陵區三峽壩區35歲以上就地後靠移民與非移民的2型糖尿病患病情況,分析其影響因素.方法 採用多階段整群隨機抽樣的方式,于2007年9-12月在湖北省宜昌市夷陵區調查瞭35歲以上農村居民9865名,其中移民1949名,非移民7916名.問捲調查收集瞭調查對象的人口學特徵、移民信息、生活方式,以及糖尿病、高血壓等慢性病信息.採集空腹8h靜脈血,檢測FBG、TG、TC、HDL-C、LDL-C.對空腹血糖≥6.1 mmol/L的調查對象進行葡萄糖負荷後2h血糖檢測.同時測量身高、體重、腰圍、臀圍1和血壓.用2000年全國人口普查數據對2型糖尿病患病率進行標準化.採用多因素logistic迴歸方法分析2型精尿病的相關因素.結果 非移民2型糖尿病患病率為3.93% (310/7885),男性為3.90% (129/3304),女性為3.95%( 181/4581);移民的糖尿病患病率為6.55%(127/1939),男性為6.85%( 52/759),女性為6.36%(75/1180),移民的糖尿病患病率高于非移民(總體比較:x2=25.10,男性比較:x2=12.59,女性比較:x2=12.78,P值均<0.01).移民和非移民的糖尿病標化患病率分彆為6.63%和4.01%;非移民男性2型糖尿病標化患病率為3.87%,女性為4.15%;移民男性2型糖尿病標化患病率為6.92%,移民女性為6.33%.多因素logistic迴歸分析結果顯示,年齡增長(相比35~ 44歲,45~54歲:OR=1.45,95% CI:1.07~1.95;55 ~64歲:0R=2.08,95%C1:1.53 ~2.84;≥65歲:OR=1.85,95% CI:1.25~2.75)、糖尿病遺傳史(OR =2.83,95% CI:1.70 ~4.72)、超重肥胖(超重:OR=1.36,95%CI:1.05 ~ 1.78;肥胖:OR=2.11;95% CI:1.47~3.01)、中心性肥胖(OR=1.84;95% CI:1.39~2.44);TG異常(OR=1.54,95%CI:1.21~1.97);TC異常(OR=1.40;95% CI:1.11~1.77);LDL-C異常(OR=1.82,95% CI:1.19~2.79)是2型糖尿病危險因素.經常、規律體力活動(OR =0.57,95% CI:0.45 ~0.72)是2型糖尿病的保護因素.結論 移民2型糖尿病患病率高于非移民;年齡、體力活動、糖尿病遺傳史、超重肥胖、中心性肥胖、TG、TC、LDL-C是2型糖尿病的影響因素.
목적 조사호북의창시이릉구삼협패구35세이상취지후고이민여비이민적2형당뇨병환병정황,분석기영향인소.방법 채용다계단정군수궤추양적방식,우2007년9-12월재호북성의창시이릉구조사료35세이상농촌거민9865명,기중이민1949명,비이민7916명.문권조사수집료조사대상적인구학특정、이민신식、생활방식,이급당뇨병、고혈압등만성병신식.채집공복8h정맥혈,검측FBG、TG、TC、HDL-C、LDL-C.대공복혈당≥6.1 mmol/L적조사대상진행포도당부하후2h혈당검측.동시측량신고、체중、요위、둔위1화혈압.용2000년전국인구보사수거대2형당뇨병환병솔진행표준화.채용다인소logistic회귀방법분석2형정뇨병적상관인소.결과 비이민2형당뇨병환병솔위3.93% (310/7885),남성위3.90% (129/3304),녀성위3.95%( 181/4581);이민적당뇨병환병솔위6.55%(127/1939),남성위6.85%( 52/759),녀성위6.36%(75/1180),이민적당뇨병환병솔고우비이민(총체비교:x2=25.10,남성비교:x2=12.59,녀성비교:x2=12.78,P치균<0.01).이민화비이민적당뇨병표화환병솔분별위6.63%화4.01%;비이민남성2형당뇨병표화환병솔위3.87%,녀성위4.15%;이민남성2형당뇨병표화환병솔위6.92%,이민녀성위6.33%.다인소logistic회귀분석결과현시,년령증장(상비35~ 44세,45~54세:OR=1.45,95% CI:1.07~1.95;55 ~64세:0R=2.08,95%C1:1.53 ~2.84;≥65세:OR=1.85,95% CI:1.25~2.75)、당뇨병유전사(OR =2.83,95% CI:1.70 ~4.72)、초중비반(초중:OR=1.36,95%CI:1.05 ~ 1.78;비반:OR=2.11;95% CI:1.47~3.01)、중심성비반(OR=1.84;95% CI:1.39~2.44);TG이상(OR=1.54,95%CI:1.21~1.97);TC이상(OR=1.40;95% CI:1.11~1.77);LDL-C이상(OR=1.82,95% CI:1.19~2.79)시2형당뇨병위험인소.경상、규률체력활동(OR =0.57,95% CI:0.45 ~0.72)시2형당뇨병적보호인소.결론 이민2형당뇨병환병솔고우비이민;년령、체력활동、당뇨병유전사、초중비반、중심성비반、TG、TC、LDL-C시2형당뇨병적영향인소.
Objective To explore type 2 diabetes prevalence and its risk factors among migrants and nonmigrants aged 35 years and older in Three Gorge Dam area in Yichang City of Hubei province,China.Methods A sample of 9865 rural residents ( including 1949 Three Gorge Dam migrants and 7916 nonmigrants ) aged 35 years old and over was selected from September to December in 2007 by the method of multi-stage cluster random sampling in Yiling district,Yichang City of Hubei province.The study subjects were assessed by interview, examination, and blood samples.Information on demographics, migrant information,lifestyle,history of diabetes and hypertension was obtained by a questionnaire interview.An overnight fasting blood specimen was collected to measure serum glucose,total cholesterol,triglyceride,high-density lipoprotein cholesterol ( HDL-C ) and low density lipoprotein-cholesterol (LDL-C).Height,weight,waist circumference,hip circumference and blood pressure were measured.Oral glucose tolerance test (OGTT) was carried out for those whose fasting glucose was equal to or exceeded 6.1 mmol/L.The standardized prevalence of type 2 diabetes was calculated based on national census in the year of 2000.Multiple logistic regression analysis was used to explore the potential risk factors of type 2 diabetes.Results The crude prevalence of type 2 diabetes among nonmigrants was 3.93% ( 310/7885 ) ( male:3.90% ( 129/3304),female:3.95% ( 181/4581 ) ),and that of migrants was 6.55% (127/1939) ( male:6.85% (52/759),female:6.36% (75/1180)).The crude prevalence of type 2 diabetes among migrants was higher than that of nonmigrants ( x2 =25.10,P < 0.01 ( male:x2 =12.59,P < 0.01 ; female:x2 =12.78,P <0.01 ) ).The prevalence of type 2 diabetes among nomnigrants was 3.87% in males and 4.15%in females.The standardized prevalence of type 2 diabetes among migrants was 6.92% in males and 6.33% in females.Logistic regression analysis showed that age (taking 35 -44 years old as reference,45 -54 years old:OR =1.45,95 % CI:1.07 - 1.95 ; 55 - 64 years old:OR =2.08,95% CI:1.53 - 2.84 ; 65 years old and over:OR =1.85,95% CI:1.25 - 2.75 ),family history of diabetes ( OR =2.83,95% CI:1.70 - 4.72 ),overweight or obesity ( overweight:OR =1.36,95% CI:1.05 - 1.78; obesity:OR =2.11,95% CI:1.47 -3.01 ),central obesity ( OR =1.84,95% CI:1.39 - 2.44 ),abnormal triglyceride ( OR =1.54,95% CI:1.21 - 1.97 ),abnormal total cholesterol ( OR =1.40,95% CI:1.11 - 1.77 ) and abnormal LDL-C ( OR =1.82,95%CI:1.19-2.79) increased the risk of type 2 diabetes,and regular physical activity (OR =0.57,95% CI:0.45 -0.72 ) was the protective factor of type 2 diabetes.Conclusion The prevalence of type 2 diabetes among Three Gorge Dam migrants was higher than that of nonmigrants.Increasing age,regular physical activity,family history of diabetes,overweight or obesity,central obesity,abnormal triglyceride,abnormal total cholesterol and abnormal LDL-C were related to type 2 diabetes.