CAJ | 학술논문

目的探讨经皮穿刺氩氦刀冷冻联合支气管动脉栓塞化疗(BACE)治疗肺癌的临床效果.方法回顾性分析42例经氩氦刀冷冻联合BACE治疗的非小细胞肺癌患者的临床资料,通过联合治疗前后影像学动态观察及KPS评分变化的分析,探讨联合治疗方案的疗效.结果联合治疗后复查CT,发现肿瘤体积较治疗前明显缩小,27例患者(64.3％)肿瘤直径缩小＞50％.治疗后1个月、6个月、12个月及24个月有效率分别为78.6％、73.8％、64.3％及57.1％；患者KPS评分较治疗前显著增高；BACE后,90.5％患者出现发热,61.9％患者出现胸痛、胸闷；氩氦冷冻治疗后,35.7％患者出现轻微胀痛感,33.3％患者出现少量胸腔积液,上述症状均自行消失.结论经皮穿刺氩氦刀冷冻联合BACE方法治疗非小细胞肺癌疗效明确、并发症少.
목적 탐토경피천자아양도냉동연합지기관동맥전새화료(BACE)치료폐암적림상효과.방법 회고성분석42례경아양도냉동연합BACE치료적비소세포폐암환자적림상자료,통과연합치료전후영상학동태관찰급KPS평분변화적분석,탐토연합치료방안적료효.결과 연합치료후복사CT,발현종류체적교치료전명현축소,27례환자(64.3％)종류직경축소＞50％.치료후1개월、6개월、12개월급24개월유효솔분별위78.6％、73.8％、64.3％급57.1％；환자KPS평분교치료전현저증고；BACE후,90.5％환자출현발열,61.9％환자출현흉통、흉민；아양냉동치료후,35.7％환자출현경미창통감,33.3％환자출현소량흉강적액,상술증상균자행소실.결론 경피천자아양도냉동연합BACE방법치료비소세포폐암료효명학、병발증소.
Objective To investigate the therapeutic effect of Ar-He cryoablation combined with bronchial artery chemoembolization(BACE) in non-small cell lung cancer(NSCLC).Methods 42 NSCLC patients'data were analyzed retrospectively.They were treated by Ar-He cryoablation combined with BACE.CT image and KPS were observed dynamically to evaluate the therapeutic effect.Results Tumer minimized significantly,64.3％ minimized more than 50％.( CR + PR) ％ of post-treat in 1 month,6month,12 month and 24 month was 78.6％,73.8％,64.3％ and 57.1％ respectively.KPS of patients rise significantly than pre-treatment.After BACE,slightly fever happened in 90.5％ patients,and pectoral discomfort happened in 61.9％ patients.After Ar-He cryoablation,slightly pain happened in 35.7％ patients,and slightly pleural effussion happened in 33.3％ patients.All symptoms disappeared automatically several days later.Conclusions Ar-He cryoablation combined with BACE supplies an optimistic alternative for those NSCLC patients,with little complications.