CAJ | 학술논문

肿瘤组织中含有多种免疫细胞、致炎细胞因子和抗炎细胞因子,其相互作用可影响肿瘤的发生和发展,并且细胞因子可以预测肿瘤的预后.致炎细胞因子与疲劳、抑郁、认知障碍、厌食、恶液质、疼痛以及治疗引起的不良反应和耐药性有关,影响肿瘤患者的生活质量.
종류조직중함유다충면역세포、치염세포인자화항염세포인자,기상호작용가영향종류적발생화발전,병차세포인자가이예측종류적예후.치염세포인자여피로、억욱、인지장애、염식、악액질、동통이급치료인기적불량반응화내약성유관,영향종류환자적생활질량.
Cytokines can have either pro-or anti-inflammatory activity and immunosuppressive activity,depending on the microenvironment.Tumors contain immune cells and a network of pro-and anti-inflammatory cytokines,which collaborate in the development and progression of cancer.Cytokine might prove to be prognostic.The systemic effects of pro-inflammatory cytokines are associated with fatigue,depression,cognitive impairment,anorexia,cachexia,pain,toxicity of treatment and resistance to treatment,which can affect quality of life.