国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2011年
1期
15-17
,共3页
维生素D3%维生素D受体%支气管哮喘%免疫
維生素D3%維生素D受體%支氣管哮喘%免疫
유생소D3%유생소D수체%지기관효천%면역
Vitamin D3%Vitamin D receptor%Bronchial asthma%Immune
支气管哮喘在世界各国都有逐年上升的趋势,大量研究显示其发生与免疫调节有密切关系,而维生素D3在支气管哮喘有其特定免疫调节机制,可通过调节细胞因子、调节性T细胞、基质金属蛋白酶-9等对支气管哮喘起到一定作用.维生素D3对支气管哮喘免疫调节可为临床有效治疗哮喘提供一定的理论依据,并最终为支气管哮喘患儿提供新的免疫治疗方法.
支氣管哮喘在世界各國都有逐年上升的趨勢,大量研究顯示其髮生與免疫調節有密切關繫,而維生素D3在支氣管哮喘有其特定免疫調節機製,可通過調節細胞因子、調節性T細胞、基質金屬蛋白酶-9等對支氣管哮喘起到一定作用.維生素D3對支氣管哮喘免疫調節可為臨床有效治療哮喘提供一定的理論依據,併最終為支氣管哮喘患兒提供新的免疫治療方法.
지기관효천재세계각국도유축년상승적추세,대량연구현시기발생여면역조절유밀절관계,이유생소D3재지기관효천유기특정면역조절궤제,가통과조절세포인자、조절성T세포、기질금속단백매-9등대지기관효천기도일정작용.유생소D3대지기관효천면역조절가위림상유효치료효천제공일정적이론의거,병최종위지기관효천환인제공신적면역치료방법.
The morbility of bronchial asthma is gradually increasing year by year all over the world. Numerous studies have demonstrated that bronchial asthma is close related with immunoregulation. Vitamin D3 is involved to immune regulatory mechanisms in bronchial asthma, including regulating cytokine, Treg, matrix metalloproteinases-9. Considering the influence of vitamin D3 on the immune regulatory of bronchial asthma, it is provided a theory evidence that vitamin D can be used in the treatment of bronchial asthma effectivly and a novel method of immune treatment for children with bronchial asthma eventually.