CAJ | 학술논문

目的探讨血小板降低对重症急性胰腺炎(SAP)的坏死程度及预后的影响.方法将四川大学华西医院2005年1月至2006年12月收治的SAP 233例,按血小板是否为正常值,分成血小板降低组(<100×10~9/L)和血小板正常组(≥100×10~9/L),分析两组血小板变化与胰腺坏死程度及预后的关系.结果血小板计数降低组99例,占42.49%;血小板计数正常组134例,占57.51%.两组在APACHEⅡ评分、预后、有尤胰腺坏死及胰腺坏死程度有统计学意义(P<0.05),两组RANSON评分无统计学意义.结论血小板降低对提示胰腺病情程度、是否存在胰腺坏死、推测疾病预后有一定临床指导意义.
목적 탐토혈소판강저대중증급성이선염(SAP)적배사정도급예후적영향.방법 장사천대학화서의원2005년1월지2006년12월수치적SAP 233례,안혈소판시부위정상치,분성혈소판강저조(<100×10~9/L)화혈소판정상조(≥100×10~9/L),분석량조혈소판변화여이선배사정도급예후적관계.결과 혈소판계수강저조99례,점42.49%;혈소판계수정상조134례,점57.51%.량조재APACHEⅡ평분、예후、유우이선배사급이선배사정도유통계학의의(P<0.05),량조RANSON평분무통계학의의.결론 혈소판강저대제시이선병정정도、시부존재이선배사、추측질병예후유일정림상지도의의.
Objective To study the significance of the change of platelet count for the degree of necrosis and prognosis of severe acute pancreatitis. Methods The 223 cases of SAP treated in our hospital from January 2005 to December 2006 were divided into group of decreases of platelet count (<100×10~9/L) (group A) and group of normal of platelet count (≥100×10~9/L) (group B). The scores of APACHEII and Ranson, degrees of pancreatic necrosis and mortality and the degree of pan-creatic necrosis were analyzed in and compared between the 2 groups. Results There were 99 cases in group A (42.49 %). The scores of APACHEII and the degree of pancreatic necrosis and mortality and the degree of pancreatic necrosis were significantly more severe in group than in group B (P<0.05). There was no marked difference in the scores of Ranson between the two groups(P>0.05). Conclu-sion Platelet count decrease is of certain clinical significance for judging severity of pancreatitis, pan-reatic necrosis and predicting its prognosis.