CAJ | 학술논문

目的观察喷他佐辛超前镇痛用于开胸手术后肋间神经冷冻患者的效果.方法 60例进行开胸手术患者(ASA Ⅰ～Ⅱ级)随机分成两组,每组30例,A组切皮前10 min静脉缓慢推注喷他佐辛0.5 mg/kg;B组切皮前静脉推注0.9％生理盐水2ml.观察两组患者的呼吸恢复时间、睁眼时间、拔管时间；采用视觉模拟评分法(VAS)对患者术后1h、4h、8h、24 h进行疼痛程度评分；采用舒适度评分法(BCS)对患者术后1h、4h、8h、24 h进行镇静评分；比较两组患者术后7日内的不良反应.结果两组患者的呼吸恢复时间、睁眼时间、拔管时间差异无显著性；A组病人各时段的VAS评分均低于B组(P＜0.05); A组患者BCS评分高于B组(P＜0.05).结论喷他佐辛超前镇痛有助于减轻开胸手术后肋间神经冷冻患者的疼痛不适,且不会导致患者苏醒延迟.
목적 관찰분타좌신초전진통용우개흉수술후륵간신경냉동환자적효과.방법 60례진행개흉수술환자(ASA Ⅰ～Ⅱ급)수궤분성량조,매조30례,A조절피전10 min정맥완만추주분타좌신0.5 mg/kg;B조절피전정맥추주0.9％생리염수2ml.관찰량조환자적호흡회복시간、정안시간、발관시간；채용시각모의평분법(VAS)대환자술후1h、4h、8h、24 h진행동통정도평분；채용서괄도평분법(BCS)대환자술후1h、4h、8h、24 h진행진정평분；비교량조환자술후7일내적불량반응.결과 량조환자적호흡회복시간、정안시간、발관시간차이무현저성；A조병인각시단적VAS평분균저우B조(P＜0.05); A조환자BCS평분고우B조(P＜0.05).결론 분타좌신초전진통유조우감경개흉수술후륵간신경냉동환자적동통불괄,차불회도치환자소성연지.
Objective To observe the effect ofpentazocine pre-emptive analgesia in patients receiving intercostal nerve cryoanalgesia after post-thoracotomy.Methods 60 patients with elective thoracotomy (ASA grade Ⅰ to grade Ⅱ ) were randomly divided into pre-emptive analgesia group (group A) and the control group (group B).Group A (n=30)received slow bolus injection of pentazocine 0.5 mg/kg 10 minutes before the beginning of operation.Patients in group B (n=30) were injected with saline (0.9％,2ml).Then we recorded the spontancous breathing recovery time,eyes open time and extubation time and analgesia.Visual analong scale scores (VAS) were used for pain degree score evaluation,and also 8CS at 1,4,8,24 hours after operation.We recorded the incidence of disadvantage between the two groups.Results There was no significant difference on the spontaneous breathing recovery time,eyes open time and extubation time between the two groups.VAS of group A was lower than that of group B (P＜0.05).BCS of group A was higher than thatof group B (P＜0.05).The incidence of disadvantage in group A was lower than that in group B (P＜0.05).Conclusion Preoperative application of pentazocine 0.5 mg/kg can effectively reduce the pain of post-thoracotomy patients receiving intercostal nerve cryoanalgesia and will not lead delayed recovery.