CAJ | 학술논문

目的研究眼反应分析仪(ORA)测量的角膜生物力学指标角膜滞后量(corneal hysteresis,CH)和角膜阻力因子(corneal resistance factor,CRF)在近视人群中的测量值以及在不同程度近视患者之间的差异.方法对357例692只眼近视患者,分为轻度近视组(≤-3.00 D)、中度近视组(-3.00～ -6.00 D)、高度近视组(-6.00 D～-10.00 D),超高度近视组(≥-10.00 D),利用眼反应分析仪测量各组CH、CRF值及超声角膜测厚仪测量中央角膜厚度(central corneal thickness,CCT),并对测量结果进行统计学分析.结果全部患者平均CH值为(10.51±1.54) mm Hg(1 kPa=7.5 mm Hg),CRF值为(10.61±1.63)mm Hg,平均CCT值(533.24±32.14)μm.轻、中度近视组CH值与高、超高度近视组比较差异具有统计学意义(P＜0.05),轻、中度近视组CRF值超高度近视组比较差异具有统计学意义(P＜0.05).各组CCT值对比差异无统计学意义.结论随着近视程度的加深,角膜生物力学特性发生改变,角膜粘滞性及眼球硬度降低.
목적 연구안반응분석의(ORA)측량적각막생물역학지표각막체후량(corneal hysteresis,CH)화각막조력인자(corneal resistance factor,CRF)재근시인군중적측량치이급재불동정도근시환자지간적차이.방법 대357례692지안근시환자,분위경도근시조(≤-3.00 D)、중도근시조(-3.00～ -6.00 D)、고도근시조(-6.00 D～-10.00 D),초고도근시조(≥-10.00 D),이용안반응분석의측량각조CH、CRF치급초성각막측후의측량중앙각막후도(central corneal thickness,CCT),병대측량결과진행통계학분석.결과 전부환자평균CH치위(10.51±1.54) mm Hg(1 kPa=7.5 mm Hg),CRF치위(10.61±1.63)mm Hg,평균CCT치(533.24±32.14)μm.경、중도근시조CH치여고、초고 도근시조비교차이구유통계학의의(P＜0.05),경、중도근시조CRF치초고도근시조비교차이구유통계학의의(P＜0.05).각조CCT치대비차이무통계학의의.결론 수착근시정도적가심,각막생물역학특성발생개변,각막점체성급안구경도강저.
Objective To investigate the differences of the corneal hysteresis (CH) and the comeal resistance factor (CRF) among various degrees myopia patients. Methods A total of 357 myopia patients (692 eyes) were divided into mild myopia group (≤ -3.00 D),moderate myopia group (-3.00D to-6.00D), high myopia group (-6.00D to-10.00D) and heavy high myopia group (≥ -10.00D).CH and CRF was measured by ocular response analyzer (ORA) and central corneal thickness (CCT) was detected on the same time.The relationships among these group's parameters were analyzed statistically. Results The average CH value was (10.51±1.54) mmHg in all myopia groups,the average CRF value was (10.61±1.63) mmHg,the average CCT value was (533.24±32.14)μm.Significant differences were between mild myopia,moderate myopia groups and high,heavy high group (P ＜ 0.05) for CH value.In terms of the CRF value,there was significant difference among mild myopia,moderate myopia and heavy high myopia.There was no significant difference in CCT value among the groups. Conclusions With the increase of the sphere equivalence,CCT value has no obvious change,but CH and CRF value are decreased.